Cardiac Function Articles & Analysis
7 articles found
The study of cardiovascular biology is essential for understanding the mechanisms that regulate heart function and vascular health. As cardiovascular diseases remain the leading cause of death worldwide, advancements in this field offer crucial insights for developing new treatments and preventive strategies. ...
The evaluation of cardiovascular toxicity is a significant challenge in drug development. Preclinical evaluation of cardiovascular safety involves a multifaceted approach, encompassing a plethora of in vitro and in vivo endpoints. These assessments continuously evolve, aiming to mitigate the incidence of cardiovascular toxicity that may emerge during clinical trials. To shed light on the ...
The role of this potassium channel is fundamental for normal cardiac function, playing a vital role in the termination of the cardiac action potential and ultimately contributing to the heart's rhythmicity. ...
These technologies assist in detecting abnormalities, quantifying cardiac function, and streamlining workflows. While the concept of AI may seem futuristic to healthcare providers, AI is already integrated across the healthcare sector. ...
Comorbidities have a cumulative and synergistic effect on cardiac function and outcomes. [11] The elderly with HFpEF have 5.5 noncardiac comorbidities on average. [12] Aging promotes coronary microvascular endothelial abnormalities, myocardial remodeling, and dysfunction in HFpEF [13,14,15]. ...
January 6, 2022—Researchers at the Perelman School of Medicine at the University of Pennsylvania published a research paper in Science titled: CAR-T cells produced in vivo to treat cardiac injury. Heart damage or inflammation can induce fibroblasts to overproduce fibrous material, causing cardiac fibrosis, which hardens the heart muscle and impairs heart ...
This is concerning, as crude oil disrupts cardiac development, morphology, and function in embryonic fish, and cardiac impairment in salmon can have major consequences on migratory success and fitness. ...