Refine by
Central Nervous System Articles & Analysis
37 articles found
These compounds operate through various mechanisms, from enzyme inhibition to receptor modulation, targeting the complex systems that regulate heart function, blood pressure, glucose metabolism, and lipid processing. ...
This article explores the profound impact of nanotechnology on drug delivery systems and its correlation with formulation development services Enhanced Drug Delivery and Targeting One of the most significant contributions of nanotechnology to pharmaceutical formulations is its ability to enhance drug delivery and targeting. ...
Targeted Drug Delivery Targeted drug delivery systems aim to deliver drugs specifically to diseased cells or tissues while minimizing exposure to healthy cells. PEG derivatives play a crucial role in developing such systems, particularly in oncology. For instance, PEGylated liposomes and nanoparticles can be engineered to carry anticancer drugs directly to tumor ...
Understanding Sleep Apnea and Its Types Sleep apnea is a sleep-related breathing disorder that results in poor sleep quality and can lead to daytime fatigue or sleepiness, forgetfulness, and irritability. According to the Mayo Clinic, there are 3 types of sleep apnea to be aware of as follows: OSA or obstructive sleep apnea is the more common form of the disorder and affects roughly 30% of ...
This type of compound mainly acts on the central nervous system, including morphine and morphine-like drugs, esters such as procaine and benzocaine, and amides such as lidocaine and bupivacaine. ...
Development of Herpes Simplex Virus Vectors Develop HSV vectors for gene therapy of rare diseases, particularly neurological disorders, to efficiently deliver genes into the central and peripheral nervous systems. Development of Vaccinia Viral Vectors Develop highly attenuated, non-replicating, or poorly replicating vaccinia virus vectors for ...
These alkaloids bind to specific receptors in the central nervous system, effectively alleviating severe pain and inducing sedation. ...
It has function of lipid-lowering, reducing blood glucose and cancer prevention. 2.8 Okra extract: It is brown powder and its active ingredient is okra polysaccharide. Okra extract can activate the central nervous system of male organs. It is effective for prostatitis, weak male sexual function and endocrine disorders. 3 Extraction methods of ...
Through organoid technology, we understand potential viral entry points (nose, eyes), possible loss of epithelial barrier function to enter the brain/central nervous system (choroid plexus, olfactory bulb), and begin to understand the role of comorbidities Early studies of autopsy tissues identified organs harboring SARS-CoV-2. ...
It can effectively combat various ALK-secondary resistance gene mutations, and has strong central nervous system permeability, maintaining high blood concentration in brain tissues. ...
Alcohol, which is often served on festive holidays. Alcohol is a central nervous system depressant, which slows down brain activity, and can make you fall asleep faster than usual. ...
The findings, published in Nature, directly link inflammation to neural pathways that regulate behavior and provide in-depth insights into how the immune system interacts with the brain. Professor Jeffrey M. Friedman of Rockefeller University said: "We are still in the early stages of trying to understand the role of the brain in infection. ...
About: CanaQuest Medical is an award-winning, Clinical Stage/Life-Sciences company focused on the drug discovery and development of next-generation targeted therapeutics within the endocannabinoid system and specific brain receptors. The Company is focused on treating neurological conditions, such as epilepsy, anxiety, depression, and Post Traumatic Stress Disorder “PTSD,” including ...
Multiple sclerosis (MS): MS is a disease in the central nervous system (CSN). CSN is made up of the brain and spinal cord. In MS the immune system attacks the so-called myelin sheaths that covers nerve fibers. ...
Profiling mouse embryos using spatial-ATAC-seq delineated tissue-region-specific epigenetic landscapes and identified gene regulators involved in the development of the central nervous system. Mapping the accessible genome in the mouse and human brain revealed the intricate arealization of brain regions. ...
In addition, CPPs also play a significantly important role in the delivery of imaging agents, due to their excellent permeability, high affinity, and high stability, with potential applications in the diagnosis and therapy of diseases such as cancer, inflammation, diabetes, central nervous system diseases, and otologic and ocular disorders. ...
With this protocol it is possible to assess the voluntary motor function, being appropriate for patients with central nervous system pathologies and peripheral neuropathic disorders, older adults with mobility impairments, and athletes interested in rapid movement reactions and direction changes. ...
Disambiguation The process of stimulating the Vagus Nerve with micropulses of electrical current is referred to in a number of different ways. Vagus Nerve Stimulation (VNS) - Typically refers to stimulation of the nerve with a surgically implanted device and electrode. Non-invasive Vagus Nerve Stimulation (tVNS, taVNS, nVNS, LLTS) - Refers to stimulation of the vagus nerve without ...
Insulating myelin sheaths encapsulate nerve axons, thereby allowing rapid conduction of action potentials between neurons, and in addition, myelin sheaths can also provide metabolic support, physical protection, and trophic factors for neuronal axons, thereby preventing axonal degeneration. In the central nervous system, myelin is generated by ...
Since the discovery, research on the complement system and its drug development has never stopped. However, it was not until 2007, when the first C5 complement inhibitor, Sorilis®, developed by Alexion, was approved for marketing, that complement drugs became available. ...