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Chronic Inflammatory Articles & Analysis

13 articles found

ELANE Protein: A Dual-Edged Regulator of Inflammation, Immunity, and Tissue Remodeling

ELANE Protein: A Dual-Edged Regulator of Inflammation, Immunity, and Tissue Remodeling

It plays a pivotal role in the host defense system by degrading bacterial proteins, remodeling extracellular matrices, and shaping inflammatory responses. However, the same proteolytic activity that protects against pathogens can, when unregulated, contribute to tissue injury, autoimmune inflammation, and chronic disease progression. ...

ByCreative BioMart


PEGylation in Pharmaceutical Development: Enhancing Drug Efficacy and Safety

PEGylation in Pharmaceutical Development: Enhancing Drug Efficacy and Safety

As research advances, next-generation PEGylation techniques promise safer, more effective therapies for diverse diseases, from cancer to chronic inflammatory conditions. By overcoming current limitations, PEGylation will continue to play a pivotal role in the future of biopharmaceuticals. ...

ByBOC Sciences


From Inflammation to Cancer: How Chemokines Shape Modern Medicine

From Inflammation to Cancer: How Chemokines Shape Modern Medicine

These chemokines protein allows researchers to study the functional dynamics of chemokine-receptor interactions in controlled environments, facilitating the development of targeted therapies for a range of diseases, including cancer, autoimmune disorders, and chronic inflammatory conditions. One of the most significant applications lies in cancer immunotherapy. ...

ByCreative BioMart


Examining Models of Chronic Obstructive Pulmonary Disease (COPD) and their Application in Other Disease Frameworks

Examining Models of Chronic Obstructive Pulmonary Disease (COPD) and their Application in Other Disease Frameworks

In the context of respiratory diseases, numerous models have been developed, with a prominent one being that of Chronic Obstructive Pulmonary Disease (COPD). Chronic Obstructive Pulmonary Disease (COPD) Models COPD is a progressive and devastating lung disorder that is currently the third leading cause of death globally. It is characterized by persistent ...

ByCreative Bioarray


Examining Models of Chronic Obstructive Pulmonary Disease (COPD) and their Application in Other Disease Frameworks

Examining Models of Chronic Obstructive Pulmonary Disease (COPD) and their Application in Other Disease Frameworks

In the context of respiratory diseases, numerous models have been developed, with a prominent one being that of Chronic Obstructive Pulmonary Disease (COPD). Chronic Obstructive Pulmonary Disease (COPD) Models COPD is a progressive and devastating lung disorder that is currently the third leading cause of death globally. It is characterized by persistent ...

ByCreative Bioarray


The Role of MMP-3: Insights into Disease Progression and Therapeutic Potential

The Role of MMP-3: Insights into Disease Progression and Therapeutic Potential

Clinical Applications of MMP-3 MMP-3 and Rheumatoid Arthritis (RA) Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease characterized by synovial cell proliferation and infiltration of lymphocytes, leading to destruction of joint cartilage and bone erosion. ...

ByBeta Lifescience


In Silico Development of Combinatorial Therapeutic Approaches Targeting Key Signaling Pathways in Metabolic Syndrome

In Silico Development of Combinatorial Therapeutic Approaches Targeting Key Signaling Pathways in Metabolic Syndrome

Hypertrophy and hyperplasia of the adipocytes result in metabolic alterations and in the onset of a low grade chronic inflammatory state (14) due to the release of pro-inflammatory adipokines from adipose tissue that can trigger insulin resistance and diabetes mellitus leading to a sequentially increased cardiovascular risk (15). ...

ByVeriSIM Life


Too much sugar consumed at a young age can harm the brain and lead to mental disorders

Too much sugar consumed at a young age can harm the brain and lead to mental disorders

Patients with psychiatric problems have a profile of enhanced pro-inflammatory cytokines and increased oxidative stress, according to data. ...

ByCreative Biolabs


Reconstruction of tissues affected by Pilonidal Sinus Disease

Reconstruction of tissues affected by Pilonidal Sinus Disease

It saw six patients undergo surgical reconstruction to treat chronic PSD using a Myriad Matrix™ device as an implant under an advanced soft tissue flap. Only one minor postoperative wound complication was observed that went on to resolve without requiring any additional surgical intervention. PSD is a chronic inflammatory disease affecting ...

ByAroa Biosurgery Limited


Cryotherapy - Baby It’s Cold Inside

Cryotherapy - Baby It’s Cold Inside

Health Benefits Attributed to Whole Body Cryotherapy Whole body cryotherapy is used to treat patients suffering from chronic inflammatory conditions, as well as, Olympic and other elite athletes experiencing muscle soreness, and to shorten recovery times from injuries and surgeries. ...

ByPureAire Monitoring Systems, Inc


Oxygen therapy for rheumatology

Oxygen therapy for rheumatology

HBOT is a very effective adjunctive treatment for Rheumatoid Arthritis procedures Rheumatoid arthritis is a chronic inflammatory autoimmune disorder that can affect the lining of the joints and cause painful swelling that will result in the erosion of bones and the deformation of joints, which aggravated, leads to physical disabilities. ...

ByOXYHELP INDUSTRY


7 Medical Calculators for Celiac Disease Diagnosis - Case Study

7 Medical Calculators for Celiac Disease Diagnosis - Case Study

This case study is presented to highlight how medical calculators can be useful clinical decision making tools for celiac disease diagnosis. Throughout the discussion, links to medical calculators that healthcare providers can use are provided. Incorporating these resources into a clinician’s workflow can lead to better outcomes through more accurate diagnoses and better management for this ...

ByThe Medical Algorithms Company Limited


Effect of combined Low-Dose Radon- and Hyperthermia Treatment (LDRnHT) of patients with ankylosing spondylitis on serum levels of cytokines and bone metabolism markers: a pilot study

Effect of combined Low-Dose Radon- and Hyperthermia Treatment (LDRnHT) of patients with ankylosing spondylitis on serum levels of cytokines and bone metabolism markers: a pilot study

Combined Low-Dose Radon- and Hyperthermia Therapy (LDRnHT) causes pain reduction in patients with AS and induces the cytokine transforming growth factor-β1 (TGF-β1). TGF-β1 acts as an anti-inflammatory cytokine and influences the OPG/RANK/RANKL system. We therefore performed a study on 33 AS patients to investigate the effect of LDRnHT on serum levels of bone metabolism markers ...

ByInderscience Publishers

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