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Cornea Articles & Analysis
20 articles found
Origin and Characteristics Derived from the limbal region of the cornea, HCEC-12 cells retain many properties of native corneal epithelial cells. ...
Human corneal epithelial cells play a vital role in maintaining the health and function of the cornea, the transparent front part of the eye. This layer of cells acts as a protective barrier against environmental insults, pathogens, and mechanical injury. ...
The three main components of tissue engineering applications are scaffold, cell and growth-stimulating signals. Collagen has been widely used in the clinical field due to its abundance in nature, biocompatibility, low antigenicity and biodegradability. In addition, the high tensile strength and fibril-forming ability of collagen enable it to be made into various forms such as tissue grafts, ...
One researcher used polystyrene microspheres to rapidly enumerate Staphylococcus aureus parasitic on human cornea and conjunctiva. Another researcher incubated fluorescent microspheres with vancomycin, combined with the ligase on the bacterial cell wall through hydrogen bonds and effectively identified live or dead bacteria in solution through the diffusion of fluorescent ...
'Overall, our results strongly suggest that intramuscular immunization of mice with the live-attenuated VC2 vaccine strain significantly alters the infiltration of γδ T cells in the corneas of ocularly-challenged mice. Furthermore, these results suggest that a vaccine-generated tissue-specific memory response significantly protects against HSV-1 immunopathogenesis. ...
This is why they are found in synovial fluid, articular cartilage, heart valves (chondroitin sulfate, the most abundant GAG in the body), skin, pulmonary arteries and liver (heparin with anticoagulant function), tendons and lungs (dermatan sulfate) and cornea and bone (keratin ...
Abstract Purpose This case report demonstrates the effectiveness of a combined unique soft contact lens design and hypertonic saline at reducing corneal edema symptoms. In addition, this case shows that using tomographic data is invaluable for detecting and monitoring of these presentations. ...
Collagen is mainly found in connective tissues of the human body such as skin, internal organs, tendons, cornea, cartilage and bones. Collagen is a very important protein in the human body, accounting for about 30% of the total protein content. ...
Aramis Biosciences announced that the first patient has been dosed in its phase 2 proof of concept clinical trial evaluating A197, a novel, first-in-class, topical immunomodulatory agent for the treatment of dry eye disease. “This is an important milestone for Aramis Biosciences and a hopeful moment for dry eye patients given the suboptimal efficacy and tolerability limitations commonly ...
Although post-mortem brains have been frequently reported as the "gold standard" in transcriptomic research for ND and neuropsychiatric abnormalities, the main sources has been mRNA separated from transgenic animal models and, more lately, patient-derived cell lines. However, despite their promise, transcriptome studies are difficult due to the obvious difficulties in obtaining brain tissue and ...
Methods: The EndoArt (EyeYon Medical, Israel) is a flexible, 50-μm thin artificial endothelial layer that matches the cornea’s posterior curvature and functions as a fluid barrier at the posterior stroma, replacing the diseased endothelium. ...
Abstract Introduction. To compare the safety and efficacy of the Therapeutic Hyper-CL™ lens versus a standard bandage contact lens (PureVision B&L) for chronic corneal edema. Methods. Prospective, multicenter, randomized, crossover study. Chronic corneal edema patients were randomized to one of two arms. The first arm was fitted with the Therapeutic Hyper-CL™ lens while the ...
It works by partially sealing the posterior cornea, decreasing the flow of liquid and establishing a new equilibrium to maintain metabolism. This initial study had two principal goals, explained Dr Lapid-Gortzak: to demonstrate the adherence of the EndoArt to the cornea and establish a thinner cornea over the follow-up period. The inclusion ...
In contrast, HSV-1 (F)-vaccinated mice developed time-dependent progressive keratitis characterized by corneal opacification, while mock-vaccinated animals exhibited more severe stromal keratitis characterized by immune cell infiltration and neovascularization in corneal stroma with corneal opacification. Cornea in VC2-immunized mice exhibited significantly increased infiltration ...
A nonfunctioning endothelium results in corneal homeostasis loss due to excess fluid flowing into the cornea, resulting in severe vision loss. The minimally invasive, suture-free EndoArt® is designed to replace dysfunctional endothelium in those patients where human donor tissue, which is the current standard of care, has failed to resolve the edema. ...
Mojo Vision's lens display, however, could follow my eye everywhere, because it would be on my cornea. "The Mojo Lens will be able to help people who have low-vision conditions, like macular degeneration, glaucoma, retinitis pigmentosa, which is a type of tunnel vision, night blindness," Sinclair said. ...
Product Details A complete line of Ophthalmic Surgical Knives includes Stab Knife, Slit Knife and Clear Cornea Knife, Parallel Side Knife, Trapezoid Knife, Implant Knife, Round Tunnel Knife and Crescent Tunnel Knife. ...
The cornea is essential for vision yet highly sensitive to immune-mediated damage following infection. ...
The thickness in the central region of the lens is used because this covers the most critical area of the cornea. The highest permeability materials are difficult to manufacture into thin lenses, resulting in a range of designs. ...
The results show that for photon sources with energies lower than 30 keV, the attenuations by the eyelid are relevant in reducing the dose in the eye lens and cornea. This suggests that medical exposure protocols that use this energy range should consider advising patients to close their eyes during the exposure.Keywords: Monte Carlo simulation, absorbed dose, radiology, GEANT4, ...