Detection Of Biomarker Articles & Analysis
20 articles found
The Technical Revolution in Glycan Analysis Modern glycomics leverages breakthrough technologies that have transformed the field: Nano-LC-MS/MS with electron-transfer dissociation capturing fragmentation patterns impossible with earlier techniques Isotope-coded glycan tagging enabling precise quantitative comparisons across disease states MALDI-imaging mass spectrometry visualizing glycan ...
PEG-modified nanoparticles can be used as biomarkers for detecting and imaging biomolecules. Carboxylic acid PEGs can be combined with markers such as fluorescent dyes or radionuclides to achieve high-resolution imaging and fluorescent labeling in vivo. ...
The accurate and timely diagnosis of preeclampsia is critical in management of affected pregnancies to reduce maternal and fetal/neonatal morbidity and mortality, yet difficulties remain in establishing the rigorous diagnosis of preeclampsia based on clinical parameters alone. Biomarkers that detect biochemical disease have been proposed as complements or ...
From one cell division to the next, epigenetic DNA and chromatin modifications prevail and can happen for several generations of cells. Biomarkers for the detection of certain metabolic diseases could be methylated DNA, acetylated proteins, miRNA, specific substrates, cofactors, enzymes engaging in biochemical reactions linked to epigenomic procedures in body ...
The application of existing WGS technologies to rare disease cases has proven to be useful in identifying the cause of disease by detecting multiple and comprehensive mutations at the whole-genome level, providing invaluable insights into the underlying molecular mechanisms of various rare diseases and opening up new possibilities for personalized medicine. ...
Differential expression analysis Differential gene expression (DGE) analysis is a key part of the analysis of small RNA data, which helps predict targets and find biomarkers.There are several good tools for this purpose (Table 3), but the optimal tool is highly dependent on the specific dataset. Biomarker identification and target prediction Biomarker ...
Despite the skepticism surrounding its viability in a clinical setting, QSM shows great potential in a wide range of clinical applications, particularly for biomarker detection and ...
To understand the significance of the SpinTech MRI STAGE software platform, it helps to begin by asking a question: Given that MRI is an incredibly powerful diagnostic tool for neurological diseases like Alzheimer’s, dementia, Parkinson’s and multiple sclerosis (MS), why have radiologists and neurologists had to choose between conducting faster MRI exams and obtaining higher-quality ...
Urine E-cadherin was supposed to be a marker for early detection of kidney injury in diabetic patients. In Sun’s research, label-free quantification was applied to systematically compare the protein profiling in saliva and serum exosomes from healthy subjects and lung cancer patients, and potential candidates were discovered as biomarkers for lung cancer. ...
Our lipidomics analysis platform can detect cancer biomarkers, analyze the role and specific mechanisms of genes related to lipid metabolism in cancer, and investigate the signaling pathways that may be involved. ...
Pathology AI algorithms can help pathologists diagnose diseases with greater efficiency and accuracy, as well as detect biomarkers that can inform patient treatment at the point of diagnosis. Working toward establishing coding and payment for these downstream procedures as well will allow clinicians and patients to fully reap the benefits of AI for pathology, ...
Recently, in a study published in the journal Scientific Reports entitled "Epigenome association study for DNA methylation biomarkers in buccal and monocyte cells for female rheumatoid arthritis", scientists from Washington State University found through the study that cells from cheek wipes may reveal biomarkers of rheumatoid arthritis, which may help develop a ...
Digital biomarkers are functional measures, which may translate better to the measures collected in clinical trials than histology alone. Digital biomarkers including breathing rate are calculated from 24/7 monitoring of subjects in home environments. ...
Serum and urine Gal-3 levels were reliable biomarkers for detecting AKI (AUC: 0.88 and 0.87). In the rat renal I/R injury model, I/R caused an increase of Gal-3 at 0.5 h after reperfusion (p < 0.05). ...
SEVILLE, Spain--(BUSINESS WIRE)--Universal Diagnostics (UDX), an in-vitro diagnostics company developing minimally-invasive, blood-based solutions for detecting cancer early, announced today that it has started a prospective, multi-center observational study in the US for its investigational advanced adenoma (precursor lesions) and colorectal cancer (CRC) ...
NEW YORK - Spanish cancer research firm Universal Diagnostics is gearing up to commercialize a liquid biopsy test that applies methylation biomarkers to detect lung cancer, based on data presented at the International Association for the Study of Lung Cancer 2020 World Conference for Lung Cancer (WCLC) last month. ...
Abstract Purpose: SelectMDx (MDxHealth®) is a panel of urinary biomarkers used in conjunction with traditional risk factors to individualize risk prediction for clinically significant prostate cancer. ...
In fact, these devices have demonstrated the ability to detect a variety of analyses such as particular DNA sequences, cancer biomarkers and larger entities such as viruses. ...
Although intersex of fish species has been widely reported in aquatic environments, there is no appropriate biomarker of the effects to assess the occurrence of intersex. In the present study, mRNA expression profiles of 14 genes, which are either involved in ovary development and maintenance or have relatively high mRNA transcription levels in ovarian gene expression profiles in fish species, ...
Organic contaminants are continually entering aquatic environments and thence the tissues of resident biota. Mussels and other molluscs are used worldwide as sentinels in pollution monitoring. Recent years have seen the development of biological measurements (biomarkers) as tools for use in monitoring and environmental impact assessment, such biomarkers being indicative of contaminant exposure ...