Refine by
Diabetes Articles & Analysis: Older
201 articles found
This approach is particularly valuable in developing drugs that target glycosylation pathways, which are implicated in a wide range of diseases, including cancer, diabetes, and inflammatory disorders. Microarray-based screening allows for high-throughput testing of a large number of compounds for their ability to interact with specific glycan structures, accelerating the drug ...
Research also highlights the importance of corneal epithelial cells in the context of systemic diseases. Conditions such as diabetes and autoimmune disorders can affect the health of the cornea and, by extension, the epithelial cells. ...
This function is particularly important in the context of metabolic disorders such as obesity and type 2 diabetes. Impaired endothelial function in muscle microvasculature can lead to reduced insulin sensitivity and glucose uptake, further exacerbating metabolic dysregulation. ...
Slow movement through the intestines allows bacteria to grow, causes of this can be: · History of food poisoning · Diabetes · Certain medications · Nerve damage However, in some cases, the cause can be unknown. ...
Secretome field can be used to study the regulation and interaction of these pathways.Functional AnalysisThe secretome field also involves understanding the biological functions of secreted proteins, such as how they mediate cell communication, participate in immune responses, regulate metabolism, and affect disease progression.Disease ResearchSecreted proteins are related to many diseases, such ...
In certain disease states, especially in patients with diabetes, the production of glycated collagen increases due to elevated blood glucose levels. ...
Glycosylation plays a critical role in organisms, but it may also be associated with certain diseases such as diabetes and cancer.As a common post-translational modification, glycosylation plays a crucial role in protein function and cell communication. ...
Moreover, glycoproteins are involved in the onset and progression of many diseases, such as cancer, diabetes, neurodegenerative diseases, etc.What Is the TAP Detection ...
Furthermore, changes in the mitochondrial proteome may be associated with certain diseases, including neurodegenerative diseases, cancer, heart disease, diabetes, and genetic disorders.Methods of Mitochondrial Protein SequencingMitochondrial protein sequencing typically involves the following steps: firstly, scientists need to extract the mitochondria from cells and isolate the ...
At present, peptide drugs have shown broad application prospects in the treatment of tumors, hepatitis, diabetes, and AIDS.Antibody-Based TherapyAntibodies are proteins produced by the immune system that can bind to specific markers on cells or tissues. ...
Dysregulation of sugar nucleotide metabolism has been implicated in a number of diseases, including cancer, diabetes, and congenital disorders of glycosylation. In these conditions, the altered availability of specific sugar nucleotides can lead to the synthesis of aberrant glycans with impaired function. ...
Currently, peptide drugs are widely used in the diagnosis and treatment of tumors, autoimmune diseases, certain cardiovascular diseases, diabetes, etc., with broad application prospects. However, in the research and production process of peptide drugs, precise analysis must be performed to determine their purity, structure, charge, and other characteristics to ensure their ...
Currently, peptide drugs are widely used in the diagnosis and treatment of tumors, autoimmune diseases, and certain cardiovascular diseases and diabetes, with broad application prospects.Analytical Ultracentrifugation (AUC) has a wide range of applications in peptide drug research and development. ...
Disturbances in metabolic pathways can lead to many common human diseases such as cancer, diabetes, obesity, hypoglycemia, hypolipidemia, phenylketonuria, neurodegeneration, etc. ...
MMP-9 has also been proposed as a therapeutic target for Alzheimer's disease and type 2 diabetes. Neuronal MMP-9 is involved in synaptic plasticity by controlling the shape of dendritic spines and the function of excitatory synapses, thus playing a key role in learning, memory and cortical plasticity. ...
For instance, prolidase-based wound dressings have shown promising results in accelerating the healing of chronic wounds, such as those associated with diabetes or venous insufficiency. Furthermore, the enzyme is being investigated for its potential to enhance the bioavailability and efficacy of certain drugs, leading to improved therapeutic outcomes. ...
Dysbiosis of the intestinal flora is associated with a variety of human metabolic diseases, such as obesity, diabetes mellitus, and nonalcoholic fatty liver disease. Regulation of lipoprotein metabolism by intestinal flora The intestine is not only a site of lipid digestion and absorption, but also a place where a large number of microorganisms reside. ...
This technology has revolutionized the treatment of chronic conditions, such as diabetes, hypertension, and cancer, by providing patients with a steady supply of medication over an extended period of time. ...
For instance, studying the enzymes involved in carbohydrate synthesis can help researchers develop new drugs and therapies for metabolic disorders, such as diabetes. By targeting specific enzymes, it may be possible to regulate carbohydrate metabolism and improve glucose homeostasis in individuals with diabetes. ...
Diabetes is a common clinical disease, and with the improvement of living standards, an increase in the number of obese people, and the intensification of aging populations, the incidence of diabetes is increasing year by year. Diabetes has various types and requires long-term treatment. Antidiabetic drugs are essential for people with the ...