Refine by
Diabetes Articles & Analysis
212 articles found
In soft tissues like arteries, unregulated hydroxyapatite accumulation leads to vascular calcification, a pathological condition associated with atherosclerosis, diabetes, chronic kidney disease (CKD), and aging. Studies in MGP-knockout mice have shown extensive arterial calcification and premature death, underscoring the importance of this protein in maintaining vascular ...
Dysfunction of podocytes is linked to various kidney diseases, including diabetic nephropathy, focal segmental glomerulosclerosis, and minimal change disease. ...
If you ignore the snoring and sleep apnea, it can lead to multiple health issues such as hypertension, cardiovascular issues and even Type 2 diabetes. Usually, the gold standard in sleep apnea treatment is CPAP therapy or Continuous Positive Airway Pressure therapy, which helps eliminate the pauses in breathing, as it provides a steady stream of air to your airways, with the ...
Weight and sleep interconnected and that fact is oftentimes overlooked. If you are having issues sleeping or wake up frequently at night, did you gain weight recently? If you have, you are not alone. Many studies have shown that weight gain does lead to poor sleep and can impact REM sleep, due to hormonal imbalances and sleep disorders, such as sleep ...
The Role of Podocytes in Kidney Disease Recent research has highlighted the importance of podocytes in various renal pathologies. Conditions such as diabetic nephropathy, focal segmental glomerulosclerosis, and nephrotic syndrome are characterized by podocyte injury or loss. ...
Hypoglycemic APIs: Controlling Diabetes Effectively Diabetes management has been revolutionized by hypoglycemic APIs, which play an integral role in controlling blood glucose levels. These APIs are specially designed to combat the symptoms of diabetes, a chronic condition characterized by hyperglycemia. A diverse range of ...
A New Drug to Reduce Heart Attacks and Strokes The newly approved drug Sotagliflozin (Inpefa) has shown promise in reducing heart attacks and strokes among patients with type 2 diabetes and chronic kidney disease. It works as a dual SGLT1 and SGLT2 inhibitor, helping to regulate blood sugar levels while also protecting the heart. ...
Disease Research: By mapping altered flux patterns in cancer cells, cardiovascular diseases, or diabetes, MFA helps identify potential metabolic vulnerabilities or biomarkers for diagnosis and therapy. ...
Moreover, lipidomic shifts can also reveal insights into metabolic conditions such as obesity, diabetes, and neurodegenerative diseases. For instance, certain lipid species found in exosomes may indicate disrupted signaling pathways or abnormal cellular function, providing opportunities for therapeutic intervention. ...
Metabolic Health and Disease Research Alterations in NAD/NADH levels are associated with a wide range of diseases, including cancer, diabetes, neurodegenerative disorders (e.g., Alzheimer’s and Parkinson’s), and mitochondrial diseases. ...
This process enables researchers to identify compounds that can modulate receptor activity, which is particularly relevant in the treatment of various diseases, including cancer, diabetes, and cardiovascular disorders. By observing the effects of different compounds on nuclear receptors, scientists can gain insights into the mechanisms of disease and develop targeted therapies. ...
This approach is particularly valuable in developing drugs that target glycosylation pathways, which are implicated in a wide range of diseases, including cancer, diabetes, and inflammatory disorders. Microarray-based screening allows for high-throughput testing of a large number of compounds for their ability to interact with specific glycan structures, accelerating the drug ...
This function is particularly important in the context of metabolic disorders such as obesity and type 2 diabetes. Impaired endothelial function in muscle microvasculature can lead to reduced insulin sensitivity and glucose uptake, further exacerbating metabolic dysregulation. ...
Research also highlights the importance of corneal epithelial cells in the context of systemic diseases. Conditions such as diabetes and autoimmune disorders can affect the health of the cornea and, by extension, the epithelial cells. ...
Slow movement through the intestines allows bacteria to grow, causes of this can be: · History of food poisoning · Diabetes · Certain medications · Nerve damage However, in some cases, the cause can be unknown. ...
Secretome field can be used to study the regulation and interaction of these pathways.Functional AnalysisThe secretome field also involves understanding the biological functions of secreted proteins, such as how they mediate cell communication, participate in immune responses, regulate metabolism, and affect disease progression.Disease ResearchSecreted proteins are related to many diseases, such ...
Glycosylation plays a critical role in organisms, but it may also be associated with certain diseases such as diabetes and cancer.As a common post-translational modification, glycosylation plays a crucial role in protein function and cell communication. ...
In certain disease states, especially in patients with diabetes, the production of glycated collagen increases due to elevated blood glucose levels. ...
Moreover, glycoproteins are involved in the onset and progression of many diseases, such as cancer, diabetes, neurodegenerative diseases, etc.What Is the TAP Detection ...
Furthermore, changes in the mitochondrial proteome may be associated with certain diseases, including neurodegenerative diseases, cancer, heart disease, diabetes, and genetic disorders.Methods of Mitochondrial Protein SequencingMitochondrial protein sequencing typically involves the following steps: firstly, scientists need to extract the mitochondria from cells and isolate the ...