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Diabetes Articles & Analysis: This-Year
11 articles found
In soft tissues like arteries, unregulated hydroxyapatite accumulation leads to vascular calcification, a pathological condition associated with atherosclerosis, diabetes, chronic kidney disease (CKD), and aging. Studies in MGP-knockout mice have shown extensive arterial calcification and premature death, underscoring the importance of this protein in maintaining vascular ...
Dysfunction of podocytes is linked to various kidney diseases, including diabetic nephropathy, focal segmental glomerulosclerosis, and minimal change disease. ...
If you ignore the snoring and sleep apnea, it can lead to multiple health issues such as hypertension, cardiovascular issues and even Type 2 diabetes. Usually, the gold standard in sleep apnea treatment is CPAP therapy or Continuous Positive Airway Pressure therapy, which helps eliminate the pauses in breathing, as it provides a steady stream of air to your airways, with the ...
Weight and sleep interconnected and that fact is oftentimes overlooked. If you are having issues sleeping or wake up frequently at night, did you gain weight recently? If you have, you are not alone. Many studies have shown that weight gain does lead to poor sleep and can impact REM sleep, due to hormonal imbalances and sleep disorders, such as sleep ...
The Role of Podocytes in Kidney Disease Recent research has highlighted the importance of podocytes in various renal pathologies. Conditions such as diabetic nephropathy, focal segmental glomerulosclerosis, and nephrotic syndrome are characterized by podocyte injury or loss. ...
Hypoglycemic APIs: Controlling Diabetes Effectively Diabetes management has been revolutionized by hypoglycemic APIs, which play an integral role in controlling blood glucose levels. These APIs are specially designed to combat the symptoms of diabetes, a chronic condition characterized by hyperglycemia. A diverse range of ...
A New Drug to Reduce Heart Attacks and Strokes The newly approved drug Sotagliflozin (Inpefa) has shown promise in reducing heart attacks and strokes among patients with type 2 diabetes and chronic kidney disease. It works as a dual SGLT1 and SGLT2 inhibitor, helping to regulate blood sugar levels while also protecting the heart. ...
Disease Research: By mapping altered flux patterns in cancer cells, cardiovascular diseases, or diabetes, MFA helps identify potential metabolic vulnerabilities or biomarkers for diagnosis and therapy. ...
Metabolic Health and Disease Research Alterations in NAD/NADH levels are associated with a wide range of diseases, including cancer, diabetes, neurodegenerative disorders (e.g., Alzheimer’s and Parkinson’s), and mitochondrial diseases. ...
Moreover, lipidomic shifts can also reveal insights into metabolic conditions such as obesity, diabetes, and neurodegenerative diseases. For instance, certain lipid species found in exosomes may indicate disrupted signaling pathways or abnormal cellular function, providing opportunities for therapeutic intervention. ...
This process enables researchers to identify compounds that can modulate receptor activity, which is particularly relevant in the treatment of various diseases, including cancer, diabetes, and cardiovascular disorders. By observing the effects of different compounds on nuclear receptors, scientists can gain insights into the mechanisms of disease and develop targeted therapies. ...