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Disease And Recurrence Articles & Analysis

9 articles found

Using artificial intelligencepowered evidence-based molecular decision-making for improved outcomes in ovarian cancer

Using artificial intelligencepowered evidence-based molecular decision-making for improved outcomes in ovarian cancer

Background and objective High grade serous carcinoma (HGSC) of the ovary is a complex and deadly disease. Although frontline treatment of chemotherapy and surgery is often effective, with nearly all patients experiencing remission, over 80% of patients will experience disease recurrence in the first two years and ultimately die of the ...

ByPredictive Oncology Inc.


VLE for Pre-Treatment Planning - Case Study

VLE for Pre-Treatment Planning - Case Study

The intent for this procedure was to assess the treatment area, in part, using the NvisionVLE Imaging System, and to ablate any recurrence of ...

ByNinePoint Medical, Inc. (NPM)


Possible treatment of human multiple myeloma found

Possible treatment of human multiple myeloma found

Some patients with multiple myeloma often relapse due to the emergence of immune escape mutations, which makes cancer cells in the body resistant to therapy; therefore, researchers urgently need a new target antigen to develop a multi-targeted method, so as to avoid immune escape and avoid disease recurrence. In previous studies, researchers focused on ...

ByProfacgen


New Study Findings about Glycoprotein PTGDS

New Study Findings about Glycoprotein PTGDS

However, 40–50% of patients with DLBCL still present with intractable or recurrent disease and eventually die of progressive disease. Therefore, the treatment of DLBCL also needs to find more new therapeutic targets. ...

ByCD BioGlyco.


Intraoperative Radiation Therapy (IORT) with VeraForm: Marking for Variability

Intraoperative Radiation Therapy (IORT) with VeraForm: Marking for Variability

IORT using the Zeiss® Intrabeam® System has been proven to be non-inferior to External Beam Radiation Therapy (EBRT) in local recurrence and disease-free survival. IORT’s advantage is one treatment during surgery instead of several weeks of EBRT which has obvious benefits for patient convenience, compliance and quality of life. ...

ByVidera Surgical Inc.


Duration of protection from live attenuated vs. sub unit HSV-2 vaccines in the guinea pig model of genital herpes: Reassessing efficacy using endpoints from clinical trials

Duration of protection from live attenuated vs. sub unit HSV-2 vaccines in the guinea pig model of genital herpes: Reassessing efficacy using endpoints from clinical trials

Results Both VC2 and gD2 vaccines reduced acute genital disease. VC2 was somewhat more effective in reducing acute vaginal replication, the amount of virus in neural tissue, subsequent recurrent disease and recurrent virus shedding following challenge at 3 weeks post vaccination. ...

ByRational Vaccines, Inc.


Vaccine-induced antibodies target sequestered viral antigens to prevent ocular HSV-1 pathogenesis, preserve vision, and preempt productive neuronal infection

Vaccine-induced antibodies target sequestered viral antigens to prevent ocular HSV-1 pathogenesis, preserve vision, and preempt productive neuronal infection

Furthermore, the total reservoir of latent virus in the trigeminal ganglia (TG), which supply sensory innervation to orofacial mucosal sites, correlates with reactivation risk and clinical disease burden in animal models.'7'11 Chronic viral reactivation in the human eye is associated with a myriad of clinically important corneal pathologies including scarring, neovascularization, ...

ByRational Vaccines, Inc.


The HSV-1 live attenuated VC2 vaccine provides protection against HSV-2 genital infection in the guinea pig model of genital herpe

The HSV-1 live attenuated VC2 vaccine provides protection against HSV-2 genital infection in the guinea pig model of genital herpe

The guinea pig model allows evaluation of acute and recurrent disease, as well as vaginal shedding acutely and during episodes of recurrent activation. ...

ByRational Vaccines, Inc.


Regulation of cancer by therapeutic vaccination and dietary bio-modulation involving organ-specific mitochondria

Regulation of cancer by therapeutic vaccination and dietary bio-modulation involving organ-specific mitochondria

Cancer therapy should aim to prevent recurrent disease. Surgery and toxic treatments remove only symptoms associated with cancer without trying to intervene in the aetiology, therefore the disease may recur. ...

ByInderscience Publishers

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