Dna Vaccine Articles & Analysis
3 articles found
Compared with other carrier materials, PLGA nanocarriers have the following advantages: It is polymerized by glycolic acid and lactic acid, and the synthesis process is relatively mature; The nanoparticle size is controllable, uniform in size and small in dispersion; It can achieve long-term sustained release of carrier drugs (several weeks or months), reduce the frequency of medication, and ...
As of January 1, 2023, global vaccine development includes a total of 966 vaccine candidates, of which 23% (220) are traditional inactivated or attenuated vaccines. Advances in molecular technology have facilitated the development of other platforms, such as recombinant protein vaccines, nucleic acid vaccines, ...
Therefore, it is imperative that a vaccine be developed based on local circulating subtype and tested for immunogenicity in mice and non-human primate models. This paper is a review of the work done on the development and immunogenicity testing of recombinant DNA (rDNA) and recombinant MVA (rMVA) vaccine candidates in animal models under a ...