Drug Exposure Articles & Analysis
8 articles found
However, they substantially concentrate on the potential adverse effects of chemical exposure. Pharmacokinetic studies serve as the foundation for understanding the drug's bioavailability – the degree and rate at which an administered drug reaches the systemic circulation. ...
This new approach to treatment incorporates patient perspectives into drug development. A key benefit is the keener focus on convenience and safe drug administration. ...
Epigenetics is an emerging field of research that focuses on the effects of environmental factors, such as infections, pollutants, stress, and long-term drug exposure, on an individual's genome. Epigenetic changes do not alter the structure of DNA, but do alter the way DNA is modified. ...
Drug development platform, BIOiSIM™, was used to narrow down two different drug classes with distinct modes of action and modalities. ...
Prediction of the first-in-human dosing regimens is a critical step in drug development and requires accurate quantitation of drug distribution. ...
An estimated 5% of expectant mothers use illicit drugs during pregnancy. Drug use during pregnancy is associated with premature birth, low birth weight and cognitive or behavioral problems for the child. ...
The aim of the present study was to investigate the lethal and sublethal effects of prednisolone (PDS) exposure on the embryonic and post‐hatching stage of the freshwater snail, Physa acuta. ...
Title II of DQSA, the Drug Supply Chain Security Act (DSCSA) focused on building “an electronic, interoperable system to identify and trace certain prescription drugs.” Encompassing every link in the supply chain – manufacturers, repackagers, wholesale distributors, and dispensers, as well as third-party logistics providers – the ...