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Drug Integrity Articles & Analysis

10 articles found

Drug Screening in Drug-Resistant Cells: A Critical Approach to Overcoming Treatment Challenges

Drug Screening in Drug-Resistant Cells: A Critical Approach to Overcoming Treatment Challenges

This article explores the importance of drug screening in drug-resistant cells and its implications for advancing therapeutic strategies. ...

ByCreative Biogene


PLGA vs PEG Copolymers: A Deep Dive into 5 Key Performance Metrics

PLGA vs PEG Copolymers: A Deep Dive into 5 Key Performance Metrics

This characteristic makes them ideal for use in drug formulations that require prolonged exposure in the body. 2. Drug Loading CapacityAnother vital metric is the drug loading capacity of the copolymers. PLGA copolymers are known for their high drug loading capacity, accommodating both hydrophilic and hydrophobic ...

ByBOC Sciences


In Vivo PK/PD: A Comprehensive Overview

In Vivo PK/PD: A Comprehensive Overview

Pharmacodynamics: The Drug’s Effect on the Body Pharmacodynamics examines the biological and physiological effects of drugs and their mechanisms of action. ...

ByCreative Bioarray


Kangle anti-brittle technology

Kangle anti-brittle technology

Kangle anti-brittle capsule: innovative drug carrier based on patented technology In the field of pharmaceutical preparations, capsules are a common drug carrier, and their integrity and stability are crucial to ensure the effectiveness of drugs. ...

ByZhejiang Kangle Capsule Co., Ltd.


Microneedle Preparation Technologies   

Microneedle Preparation Technologies  

Additionally, 3D printing allows for the incorporation of drug payloads or sensors within the microneedles, enabling multifunctional applications. ...

ByCD Formulation


Drug-Loaded Liposomes: Tiny Spheres with Big Potential

Drug-Loaded Liposomes: Tiny Spheres with Big Potential

Loading the liposomes There are two main ways to load drugs into liposomes: Passive loading: This involves mixing the drug with the phospholipids during liposome formation. Hydrophilic drugs stay in the aqueous core, while hydrophobic drugs integrate into the lipid bilayer. ...

ByCreative Biostructure


How to Prepare Drug Microcapsules: A Holistic Approach

How to Prepare Drug Microcapsules: A Holistic Approach

A narrow particle size distribution ensures uniformity, which is essential for consistent drug release. Surface morphology, structural integrity, and drug release kinetics are also assessed to evaluate the performance of microcapsules. Advantages of Drug Microencapsulation Drug microencapsulation offers numerous ...

ByCD Formulation


A hybrid modeling approach for assessing mechanistic models of small molecule partitioning in vivo using a machine learning integrated modeling platform

A hybrid modeling approach for assessing mechanistic models of small molecule partitioning in vivo using a machine learning integrated modeling platform

Prediction of the first-in-human dosing regimens is a critical step in drug development and requires accurate quantitation of drug distribution. ...

ByVeriSIM Life


Policy Management – DCSCA – Drug Supply Chain Integrity

Policy Management – DCSCA – Drug Supply Chain Integrity

When the Drug Quality and Security Act (DQSA) was signed by President Obama on November 27, 2013, advocates hoped that the confusing patchwork of State laws governing drug pedigree and tracing would finally be replaced by a comprehensive solution for the ‘3T’s’ (Transaction History, Transaction Statement, and Transaction Information) of the increasingly complex pharmaceutical ...

ByConvergePoint


Drug effectiveness reporting and monitoring systems: discussion and prototype development

Drug effectiveness reporting and monitoring systems: discussion and prototype development

While tracking systems have been developed to decrease occurrences and consequences of medication errors in healthcare facilities, there is a growing need for similar systems to monitor drugs that have just entered the market with unknown adverse events. Between 1997 and 2005, the FDA's MedWatch system successfully identified 15 drugs with toxic side-effects; it ...

ByInderscience Publishers

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