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Drug Research Articles & Analysis: Older

176 articles found

Understanding Protein Ubiquitination and Cellular Health   

Understanding Protein Ubiquitination and Cellular Health  

How We Study the 'Ubiquitome': Ubiquitinated Proteomics Analysis Given its central role in health and disease, understanding which proteins are ubiquitinated, when, and how, is a major goal for researchers. This is the domain of Ubiquitinated Proteomics Analysis. The challenge is that ubiquitinated proteins are often present in very low amounts, making them difficult to detect in ...

ByCreative Proteomics


More Than Cholesterol: Exploring the Diverse World of Sterol Lipids   

More Than Cholesterol: Exploring the Diverse World of Sterol Lipids  

In biotechnology and agriculture, analyzing sterols can help in developing new drugs or engineering more resilient crops. Therefore, a robust Sterol Lipids Analysis service is an indispensable tool for researchers, clinicians, and drug developers. It allows them to: Diagnose and Monitor Disease: Quantifying specific sterols can serve as ...

ByCreative Proteomics


Common Types of Excipients in Pharmaceutical Formulations

Common Types of Excipients in Pharmaceutical Formulations

Binders can affect the disintegration and dissolution of tablets, thus influencing the drug's bioavailability. Diluents (Fillers): Diluents (or fillers) are inactive ingredients added to adjust the mass and volume of dosage forms. ...

ByBOC Sciences


Exploring Traditional and Innovative Techniques in Lipid Synthesis

Exploring Traditional and Innovative Techniques in Lipid Synthesis

One notable application of chemical synthesis is in the development of lipid conjugates used in drug delivery systems. Researchers can design lipids with specific hydrophilicity and hydrophobicity, enhancing the bioavailability and targeting capability of therapeutic agents. ...

ByBOC Sciences


Kinase Screening Services: Unlocking the Path to Targeted Therapeutics

Kinase Screening Services: Unlocking the Path to Targeted Therapeutics

Kinase screening services assist researchers in identifying active inhibitors, understanding kinase biology, and providing insights into the mechanisms of action of drug candidates. ...

ByCreative Bioarray


Rotary Tablet Press Buying Guide 2025

Rotary Tablet Press Buying Guide 2025

Whether it is medical research or drug manufacturing, tablet press is a vital link. Let's see how to choose the one that suits you best.Grand pack.The field of drug delivery is constantly evolving, driven by the core goal of improving therapeutic outcomes—enhancing efficacy, reducing toxicity, boosting patient compliance, and even enabling ...

ByGrand Machinery


Human tumor response to novel natural product compounds using the POAI biobank and active machine learning

Human tumor response to novel natural product compounds using the POAI biobank and active machine learning

The ACE program supports academic researchers in their early drug discovery and development initiatives by providing access to the POAI proprietary active machine learning platform and frozen patient DTC samples. ...

ByPredictive Oncology Inc.


Understanding Caco-2 Permeability Assay: A Critical Tool for Drug Development

Understanding Caco-2 Permeability Assay: A Critical Tool for Drug Development

In the realm of pharmacology and drug development, the assessment of drug permeability is essential. One of the most widely recognized in vitro models for evaluating the intestinal absorption of compounds is the Caco-2 permeability assay. ...

ByCreative Bioarray


Antibody Drug Design: Advancements and Innovations

Antibody Drug Design: Advancements and Innovations

This specificity and versatility make antibodies attractive candidates for therapeutic applications. The Evolution of Antibody Drug Design Traditional methods of drug development often involved trial-and-error approaches to identify suitable candidates. ...

ByCreative Biogene


Research on Platelet Drug Delivery System

Research on Platelet Drug Delivery System

The main focus of drug carrier research today is to identify carriers that are both safe and effective for clinical treatment applications. As treatment strategies advance researchers regularly update drug delivery systems. Traditional drug delivery systems consist of liposomes and polymer micelles together with ...

ByCD Bioparticles


Understanding the MDCK Permeability Assay: A Key Tool in Drug Development

Understanding the MDCK Permeability Assay: A Key Tool in Drug Development

The MDCK permeability assay is a critical technique employed in pharmacology and drug development to evaluate the permeability of drug candidates across epithelial cell layers. ...

ByCreative Bioarray


Bioglass: Revolutionizing Medical and Dental Applications

Bioglass: Revolutionizing Medical and Dental Applications

It is used in dressings and other wound care products. l Drug Delivery: Researchers are exploring the use of bioglass as a drug delivery system. Its porous structure allows it to be loaded with drugs, which can then be released slowly over time as the bioglass degrades. Hot Topics in Bioglass Research l 3D ...

ByMatexcel


Alfa Cytology Unveils Advanced PD-1 Inhibitor Development Service for Cancer Research

Alfa Cytology Unveils Advanced PD-1 Inhibitor Development Service for Cancer Research

“We are excited to provide researchers with access to advanced technologies and extensive support crucial for their transformative studies.” In summary, Alfa Cytology excels in delivering vital services for cancer immunotherapy and cell therapy research, enabling scientists and researchers to push the boundaries of current knowledge and develop ...

ByAlfa Cytology


Custom Knockout Cell Lines: Revolutionizing Research and Therapeutics

Custom Knockout Cell Lines: Revolutionizing Research and Therapeutics

This modeling can be invaluable for studying the pathophysiology of diseases such as cancer, neurodegenerative disorders, and metabolic syndromes. Drug Discovery and Screening: Knockout cell lines can be employed to assess the efficacy of new drugs by observing how they influence cells lacking specific genes. This approach enables researchers to ...

ByCreative Bioarray


Drug Screening in Animal Models: A Crucial Step in Biomedical Research

Drug Screening in Animal Models: A Crucial Step in Biomedical Research

By using disease models that mimic human conditions, researchers can observe how well a drug alleviates symptoms or improves health outcomes. ...

ByCreative Biogene


Introduction to 3D Printing Technology and Oral Thin Films

Introduction to 3D Printing Technology and Oral Thin Films

At the forefront of this innovation is CD Formulation, a company that caters to pharmaceutical research entities looking to develop advanced oral drug delivery systems. ...

ByCD Formulation


An Introduction to Metabolic Flux Analysis and Metabolomics Services

An Introduction to Metabolic Flux Analysis and Metabolomics Services

With the integration of isotopic tracers, such as stable isotopes of carbon (¹³C, for instance), researchers can track the paths these molecules follow through metabolic pathways. ...

ByCreative Proteomics


Unveiling the Role of Nicotinamide Adenine Dinucleotide (NAD): A Key Player in Cellular Metabolism and Disease Research   

Unveiling the Role of Nicotinamide Adenine Dinucleotide (NAD): A Key Player in Cellular Metabolism and Disease Research  

Understanding and analyzing these biomolecules has become increasingly important in areas such as disease research, biomarker discovery, and drug development. NAD and NADH are not merely passive participants in metabolism—they are regulatory molecules that influence key metabolic pathways, including glycolysis, oxidative phosphorylation, and biosynthetic ...

ByCreative Proteomics


Understanding Nuclear Receptor Screening: Unveiling the Potential of Drug Discovery

Understanding Nuclear Receptor Screening: Unveiling the Potential of Drug Discovery

High-throughput screening (HTS) has become a cornerstone of drug discovery, allowing researchers to rapidly test thousands of compounds for their ability to activate or inhibit specific nuclear receptors. ...

ByCreative Biogene


Understanding Colorectal Cancer Cell Lines: A Vital Tool in Cancer Research

Understanding Colorectal Cancer Cell Lines: A Vital Tool in Cancer Research

To advance our understanding of this disease and improve treatment strategies, researchers heavily rely on colorectal cancer cell lines. These cell lines serve as essential models for studying the biology of colorectal cancer, testing new therapies, and exploring the mechanisms of drug resistance. ...

ByCreative Bioarray

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