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Drug Research Articles & Analysis

123 articles found

Exploring Traditional and Innovative Techniques in Lipid Synthesis

Exploring Traditional and Innovative Techniques in Lipid Synthesis

One notable application of chemical synthesis is in the development of lipid conjugates used in drug delivery systems. Researchers can design lipids with specific hydrophilicity and hydrophobicity, enhancing the bioavailability and targeting capability of therapeutic agents. ...

ByBOC Sciences


Common Types of Excipients in Pharmaceutical Formulations

Common Types of Excipients in Pharmaceutical Formulations

Binders can affect the disintegration and dissolution of tablets, thus influencing the drug's bioavailability. Diluents (Fillers): Diluents (or fillers) are inactive ingredients added to adjust the mass and volume of dosage forms. ...

ByBOC Sciences


Kinase Screening Services: Unlocking the Path to Targeted Therapeutics

Kinase Screening Services: Unlocking the Path to Targeted Therapeutics

Kinase screening services assist researchers in identifying active inhibitors, understanding kinase biology, and providing insights into the mechanisms of action of drug candidates. ...

ByCreative Bioarray


Antibody Drug Design: Advancements and Innovations

Antibody Drug Design: Advancements and Innovations

This specificity and versatility make antibodies attractive candidates for therapeutic applications. The Evolution of Antibody Drug Design Traditional methods of drug development often involved trial-and-error approaches to identify suitable candidates. ...

ByCreative Biogene


Understanding the MDCK Permeability Assay: A Key Tool in Drug Development

Understanding the MDCK Permeability Assay: A Key Tool in Drug Development

The MDCK permeability assay is a critical technique employed in pharmacology and drug development to evaluate the permeability of drug candidates across epithelial cell layers. ...

ByCreative Bioarray


Bioglass: Revolutionizing Medical and Dental Applications

Bioglass: Revolutionizing Medical and Dental Applications

It is used in dressings and other wound care products. l Drug Delivery: Researchers are exploring the use of bioglass as a drug delivery system. Its porous structure allows it to be loaded with drugs, which can then be released slowly over time as the bioglass degrades. Hot Topics in Bioglass Research l 3D ...

ByMatexcel


Alfa Cytology Unveils Advanced PD-1 Inhibitor Development Service for Cancer Research

Alfa Cytology Unveils Advanced PD-1 Inhibitor Development Service for Cancer Research

“We are excited to provide researchers with access to advanced technologies and extensive support crucial for their transformative studies.” In summary, Alfa Cytology excels in delivering vital services for cancer immunotherapy and cell therapy research, enabling scientists and researchers to push the boundaries of current knowledge and develop ...

ByAlfa Cytology


Drug Screening in Animal Models: A Crucial Step in Biomedical Research

Drug Screening in Animal Models: A Crucial Step in Biomedical Research

By using disease models that mimic human conditions, researchers can observe how well a drug alleviates symptoms or improves health outcomes. ...

ByCreative Biogene


Understanding Colorectal Cancer Cell Lines: A Vital Tool in Cancer Research

Understanding Colorectal Cancer Cell Lines: A Vital Tool in Cancer Research

To advance our understanding of this disease and improve treatment strategies, researchers heavily rely on colorectal cancer cell lines. These cell lines serve as essential models for studying the biology of colorectal cancer, testing new therapies, and exploring the mechanisms of drug resistance. ...

ByCreative Bioarray


Understanding Nuclear Receptor Screening: Unveiling the Potential of Drug Discovery

Understanding Nuclear Receptor Screening: Unveiling the Potential of Drug Discovery

High-throughput screening (HTS) has become a cornerstone of drug discovery, allowing researchers to rapidly test thousands of compounds for their ability to activate or inhibit specific nuclear receptors. ...

ByCreative Biogene


In Vivo PK/PD: A Comprehensive Overview

In Vivo PK/PD: A Comprehensive Overview

When studied in living organisms, this relationship is referred to as in vivo PK/PD, a discipline that provides invaluable insights into drug behavior within a biological context. Pharmacokinetics: The Journey of a Drug The pharmacokinetic profile of a drug describes its absorption, distribution, metabolism, and excretion (ADME) processes. ...

ByCreative Bioarray


Alfa Cytology Launches Innovative Bladder Cancer Therapeutic Antibody Development Services

Alfa Cytology Launches Innovative Bladder Cancer Therapeutic Antibody Development Services

Alfa Cytology has unveiled new services focused on therapeutic antibody development for bladder cancer research.Alfa Cytology, a prominent cancer research services supplier based in New York, proudly announces the launch of its comprehensive services for bladder cancer therapeutic antibody development. ...

ByAlfa Cytology


The Role of Setmelanotide In Improving Hypercapnic Chemosensitivity and Weight Loss In Male Mice

The Role of Setmelanotide In Improving Hypercapnic Chemosensitivity and Weight Loss In Male Mice

Obesity is a significant contributor to respiratory disorders such as Obesity Hypoventilation Syndrome (OHS) and sleep apnea, both of which are characterized by reduced respiratory chemosensitivity. These conditions not only impair breathing but also exacerbate the health risks associated with obesity. Recent research from Rivera (2024) investigates the potential of setmelanotide, a ...

BySCIREQ - an emka TECHNOLOGIES Company


Understanding Human Corneal Epithelial Cells: Significance and Applications

Understanding Human Corneal Epithelial Cells: Significance and Applications

This understanding has propelled research into therapeutic strategies aimed at enhancing repair mechanisms and developing stem cell therapies. ...

ByCreative Bioarray


In Vitro Permeability Assay Kits: A Comprehensive Overview

In Vitro Permeability Assay Kits: A Comprehensive Overview

In vitro permeability assay kits play a crucial role in the field of pharmaceutical development, particularly when evaluating the absorption characteristics of drugs. These kits allow scientists and researchers to investigate how compounds permeate biological membranes, which is vital for understanding drug bioavailability. ...

ByCreative Bioarray


When is It Necessary to Develop an Oral Liquid Formulation?

When is It Necessary to Develop an Oral Liquid Formulation?

Ensuring the stability and bioavailability of the drug substance in a liquid environment remains a cornerstone of formulation science, demanding specific expertise and technological know-how. ...

ByCD Formulation


Alfa Cytology Introduces Advanced Drug Development Services for Brain Tumor

Alfa Cytology Introduces Advanced Drug Development Services for Brain Tumor

Alfa Cytology has introduced its advanced drug development services for brain tumors. Alfa Cytology, celebrated for its cutting-edge biotech solutions and extensive tumor research expertise, has recently introduced brain tumor drug development services, designed to empower researchers in understanding the intricacies and unique ...

ByAlfa Cytology


Analysis of Medium Components for Recombinant Protein Vaccines

Analysis of Medium Components for Recombinant Protein Vaccines

Since the production of recombinant protein vaccines involves the growth and expression of proteins in host cells (such as E. coli, yeast, mammalian cells or insect cells), the use of appropriate culture mediums is critical to successfully produce high-quality vaccines.Media component analysis is a crucial step in biotechnology and vaccine production. It involves detailed ...

ByMtoZ Biolabs


Optical Rotation Determination of Polypeptide Drugs

Optical Rotation Determination of Polypeptide Drugs

Peptide drugs are bioactive protein fragments composed of short chains of amino acids. ...

ByMtoZ Biolabs


GMP Grade Cytokine Needed for Cell Therapy Manufacturing

GMP Grade Cytokine Needed for Cell Therapy Manufacturing

Subsequently, Creative Bioarray provided three lots of each GMP cytokine for performance equivalence and lot-to-lot consistency testing. Product transitions from research-use products to cGMP manufacturing are easiest if GMP is available from the same supplier that provides the research-use-only (RUO) protein. ...

ByCreative Bioarray

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