Drug Stability Articles & Analysis
44 articles found
As seasonal allergies affect millions globally, the demand for advanced, reliable treatments is growing rapidly. Behind the scenes of this progress lies a powerful class of materials: fluoropolymers. While often associated with aerospace, semiconductor, and chemical industries, fluoropolymers also play a vital—yet underappreciated—role in pharmaceutical manufacturing, particularly in ...
This technique improves the pharmacokinetic and pharmacodynamic properties of drugs, enhancing their stability, solubility, and circulation time while reducing immunogenicity. ...
In our last blog, Peter discussed how AI is accelerating the drug discovery process and putting pressure on chemists, who must find ways of developing these potential drugs for subsequent testing or production. ...
ByBUCHI
Linker Optimization: The linker serves a crucial function in maintaining stability, controlling drug release, and ensuring effective delivery of the cytotoxic drug. Linkers can be cleavable or non-cleavable, each with unique advantages and challenges. Their stability in circulation and the ability to release the ...
This characteristic makes them ideal for use in drug formulations that require prolonged exposure in the body. 2. Drug Loading CapacityAnother vital metric is the drug loading capacity of the copolymers. ...
The evolution of 3D printing technology has opened up new avenues in the pharmaceutical industry, especially in the fabrication of novel drug delivery systems. One such advancement is the 3D printing of Oral Thin Films (OTFs), which are ultra-thin films used to deliver drugs via oral mucosa. ...
Role of Liposomes in Drug Delivery The structure of liposomes, consisting of an aqueous core enclosed by a lipid bilayer, allows for the encapsulation of both hydrophilic and lipophilic drugs. ...
Antibody drugs are a type of drugs that treat diseases through artificially synthesized antibodies, which bind specifically to target molecules for therapeutic purposes. Common types of antibody drugs include monoclonal antibodies, artificially synthesized antibody fragments, immunotoxins, and antibody-drug conjugates, etc. ...
Therefore, by measuring the intrinsic fluorescence of recombinant protein vaccines, it is possible to obtain information about their structure and monitor possible denaturation during the preparation and storage processes, thus assessing the stability of recombinant protein vaccines.The detection of the intrinsic fluorescence of recombinant protein vaccines is typically carried ...
Recombinant protein drugs are protein-based therapeutic drugs which are produced by using DNA recombination technology or other biotechnological methods. ...
They are designed to overcome limitations associated with peptides, such as poor stability and bioavailability by preserving or enhancing their functions. ...
Recombinant protein drugs are therapeutic protein drugs produced using DNA recombination technology or other biotechnologies. ...
The presence of these impurities can affect the efficacy, safety, and stability of drugs. Therefore, the detection and analysis of glycosylation impurities are crucial in ensuring the quality and therapeutic effectiveness of pharmaceutical products.What are Glycosylated ...
The unique properties of PEG derivatives, including their biocompatibility and ability to modify the solubility, stability, and bioavailability of drugs, make them indispensable in modern pharmacology. This article explores the diverse applications of PEG derivatives in pharmaceuticals and drug delivery, shedding light on how they are shaping the ...
Compared to protein drugs, peptide drugs also have advantages such as good stability, high purity, low production cost, and low immunogenicity. ...
This information aids in understanding the drug's mechanism of action and optimizing drug design.3. Optimization of Drug Formulations and Drug Delivery SystemsCD technology can help analyze conformational changes of drug molecules in different formulations, or their encapsulation status in carrier systems (such ...
Nanoformulation also enhances the stability of drugs. Many active pharmaceutical ingredients (APIs) are prone to degradation in the body or under certain storage conditions. ...
Antibody-drug conjugates (ADCs) represent a rapidly developing field within pharmaceutical biotechnology. ...
Applications of PEGs and Carboxylic Acid PEGs Drug Delivery PEG and its carboxylic acid derivatives have important applications in drug delivery. PEG-modified nanoparticles can enhance drug bioavailability and targeting by increasing particle stability, improving drug solubility, and reducing recognition by the ...
Influencing Factors Analysis Influencing factors analysis is an important part of stability analysis that involves identifying and studying the various factors that can affect the stability of a drug. ...