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Endocrine Disrupter Articles & Analysis

32 articles found

Cardiovascular Biology: Latest Research and Innovations

Cardiovascular Biology: Latest Research and Innovations

Understanding the Cardiovascular System The cardiovascular system comprises the heart, arteries, veins, and capillaries, which work together to transport oxygen and nutrients throughout the body. Any disruption in this system can lead to conditions such as hypertension, atherosclerosis, and heart failure. ...

ByCreative BioMart


Removal of Active Pharmaceutical Ingredients via Nyex Rosalox

Removal of Active Pharmaceutical Ingredients via Nyex Rosalox

A number of the emerging contaminants associated with having a harmful effect on the endocrine system have been recognized as endocrine disrupting chemicals. ...

ByCoftec


Using Chemcatcher to investigate the potential for remobilization of sediment-bound hormone-disrupting chemicals

Using Chemcatcher to investigate the potential for remobilization of sediment-bound hormone-disrupting chemicals

It has been well proven that endocrine-disrupting chemicals (EDCs) can accumulate in river sediments. ...

ByT.E Laboratories Ltd (TelLab)


EU Endocrine Disrupting criteria will have various implications for industry

EU Endocrine Disrupting criteria will have various implications for industry

An assessment of the legal status of the substances with evidence or potential evidence of endocrine disrupting effects showed, that most of them are already subject to a ban or restriction or are addressed under existing Community legislation, although for reasons not necessarily related to endocrine disruption. ...

ByEnhesa - Global EHS & Product Compliance Assurance


Tissue explant co‐culture model of the hypothalamic‐pituitary‐gonadal‐liver axis of the fathead minnow (Pimephales promelas) as a predictive tool for endocrine disruption

Tissue explant co‐culture model of the hypothalamic‐pituitary‐gonadal‐liver axis of the fathead minnow (Pimephales promelas) as a predictive tool for endocrine disruption

Endocrine disrupting compounds (EDCs) can impact the reproductive system by interfering with the hypothalamic‐pituitary‐gonadal (HPG) axis. While in vitro testing methods have been developed to screen chemicals for endocrine disruption, extrapolation of in vitro response to in vivo action shows inconsistent accuracy. ...

ByJohn Wiley & Sons, Ltd.


Chronic exposure to mono‐(2‐ethylhexyl)‐phthalate causes endocrine disruption and reproductive dysfunction in zebrafish

Chronic exposure to mono‐(2‐ethylhexyl)‐phthalate causes endocrine disruption and reproductive dysfunction in zebrafish

Phthalic acid esters are frequently detected in aquatic environment. In this study, zebrafish were exposed to low concentrations (0, 0.46, 4.0, and 37.5 µg/L) of mono‐(2‐ethylhexyl) phthalate (MEHP) for 81 days, and the effects on reproduction, gamete quality, plasma vitellogenin (VTG), sex steroids, and transcriptional profiles of key genes involved in steroidogenesis were investigated. The ...

ByJohn Wiley & Sons, Ltd.


The endocrine effects of dietary BDE‐47 exposure, measured across multiple levels of biological organization, in breeding fathead minnows

The endocrine effects of dietary BDE‐47 exposure, measured across multiple levels of biological organization, in breeding fathead minnows

Together, these gene expression alterations suggest the potential for BDE‐47 to disrupt endocrine signaling. There were no significant differences in plasma hormone levels, GSI, SCC or reproductive success. ...

ByJohn Wiley & Sons, Ltd.


Potential estrogenic effects of wastewaters on gene expression in Pimephales promelas and fish assemblages in streams of southeastern New York

Potential estrogenic effects of wastewaters on gene expression in Pimephales promelas and fish assemblages in streams of southeastern New York

Direct linkages between endocrine‐disrupting compounds (EDCs) from municipal and industrial wastewaters and impacts on wild fish assemblages are rare. ...

ByJohn Wiley & Sons, Ltd.


Low concentrations of dihydrotestosterone induce female‐to‐male sex reversal in the frog Pelophylax nigromaculatus

Low concentrations of dihydrotestosterone induce female‐to‐male sex reversal in the frog Pelophylax nigromaculatus

Little attention has focused on the effects of androgenic endocrine‐disrupting chemicals (EDCs) on amphibians. The present study aimed to investigate the effects of lower concentrations of the androgenic EDC 5α‐dihydrotestosterone (DHT) on gonadal differentiation and development in Pelophylax nigromaculatus, a true frog distributed widely in East Asia. ...

ByJohn Wiley & Sons, Ltd.


The risk of endocrine disruption to fish in the Yellow River catchment in China assessed using a spatially‐explicit model

The risk of endocrine disruption to fish in the Yellow River catchment in China assessed using a spatially‐explicit model

The highest exposures were in the Fen and Wei tributaries. Endocrine disruption risk from estrogens was predicted to be minimal in the main stem. ...

ByJohn Wiley & Sons, Ltd.


Endocrine disrupting effect of the UV filter benzophenone‐3 in zebrafish, Danio rerio

Endocrine disrupting effect of the UV filter benzophenone‐3 in zebrafish, Danio rerio

The chemical UV filter benzophenone‐3 (BP‐3) is suspected to be an endocrine disruptor based on results from in vitro and in vivo testing. However, studies including endpoints of endocrine adversity are lacking. The present study investigated the potential endocrine disrupting effects of BP‐3 in zebrafish (Danio rerio) in the ...

ByJohn Wiley & Sons, Ltd.


Metformin exposure at environmentally relevant concentrations causes potential endocrine disruption in adult male fish

Metformin exposure at environmentally relevant concentrations causes potential endocrine disruption in adult male fish

Interactions between insulin signaling and steroidogenesis suggest potential endocrine‐disrupting effects of metformin found in the aquatic environment. ...

ByJohn Wiley & Sons, Ltd.


Effects of progesterone and norethindrone on female fathead minnow (Pimephales promelas) steroidogenesis

Effects of progesterone and norethindrone on female fathead minnow (Pimephales promelas) steroidogenesis

As knowledge of contaminants capable of adversely modulating endocrine functions increases, attention is focused on the effects of synthetic progestins as environmental endocrine disrupters. ...

ByJohn Wiley & Sons, Ltd.


Characterization of trenbolone acetate and estradiol metabolite excretion profiles in implanted steers

Characterization of trenbolone acetate and estradiol metabolite excretion profiles in implanted steers

The environmental fate and transport of steroid growth promoters suggest potential for endocrine disrupting effects among ecological receptors; however, the initial excretion of steroid metabolites from cattle administered growth promoters has not been well characterized. ...

ByJohn Wiley & Sons, Ltd.


Persistence of endocrine disruption in zebrafish (Danio rerio) after discontinued exposure to the androgen 17β‐trenbolone

Persistence of endocrine disruption in zebrafish (Danio rerio) after discontinued exposure to the androgen 17β‐trenbolone

The aim of the present study was to investigate the effects of the androgenic endocrine disruptor 17β‐trenbolone on the sexual development of zebrafish (Danio rerio) with special emphasis on the question whether adverse outcomes of developmental exposure are reversible or persistent. An exposure scenario including a recovery phase was chosen to assess the potential reversibility of androgenic ...

ByJohn Wiley & Sons, Ltd.


Identification of inter‐specific differences in phase II reactions: Determination of metabolites in the urine of 16 mammalian species exposed to environmental pyrene

Identification of inter‐specific differences in phase II reactions: Determination of metabolites in the urine of 16 mammalian species exposed to environmental pyrene

PAHs and their metabolites have carcinogenic and endocrine disrupting effects in human and wildlife, and can have serious consequences. ...

ByJohn Wiley & Sons, Ltd.


Effects of atrazine on endocrinology and physiology in juvenile barramundi, Lates calcarifer (Bloch)

Effects of atrazine on endocrinology and physiology in juvenile barramundi, Lates calcarifer (Bloch)

Potential impacts on native fish species exposed to known endocrine disrupting chemicals such as atrazine, simazine and diuron have not been assessed. Here, we examine the endocrine and physiological effects of short‐term, acute exposure of environmentally relevant concentrations of analytical grade atrazine in juvenile barramundi (Lates ...

ByJohn Wiley & Sons, Ltd.


Endocrine disruption and reproduction impairment in zebrafish after long‐term exposure to DE‐71

Endocrine disruption and reproduction impairment in zebrafish after long‐term exposure to DE‐71

Our objective was to investigate the impact of Polybrominated diphenyl ethers (PBDEs) on fish reproduction over two generations. Zebrafish (Danio rerio) embryos (F0) were exposed to low concentrations (3, 10, 30 μg/L) of the PBDE mixture DE‐71 until they were sexually mature, and steroid hormone production, expression of genes involved in steroidogenesis, gonadal development and gamete ...

ByJohn Wiley & Sons, Ltd.


Lifelong exposure to methylmercury disrupts stress‐induced corticosterone response in zebra finches (Taeniopygia guttata)

Lifelong exposure to methylmercury disrupts stress‐induced corticosterone response in zebra finches (Taeniopygia guttata)

Mercury can disrupt the endocrine systems of mammals and fish, but little is known about its effects on avian hormones. ...

ByJohn Wiley & Sons, Ltd.


Effects of salinity acclimation on the endocrine disruption and acute toxicity of bifenthrin in freshwater and euryhaline strains of Oncorhynchus mykiss

Effects of salinity acclimation on the endocrine disruption and acute toxicity of bifenthrin in freshwater and euryhaline strains of Oncorhynchus mykiss

The pyrethroid insecticide, bifenthrin, is frequently detected at ng/L concentrations in tributaries of the San Francisco Bay Delta (SFBD). The estuary is also experiencing increasing salinity through climate change and water redirection. To evaluate the impacts of hypersaline conditions on bifenthrin toxicity in anadromous salmonids of the SFBD, a 14‐day laboratory exposure was performed ...

ByJohn Wiley & Sons, Ltd.

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