Endocrine Disruption Articles & Analysis
32 articles found
Understanding the Cardiovascular System The cardiovascular system comprises the heart, arteries, veins, and capillaries, which work together to transport oxygen and nutrients throughout the body. Any disruption in this system can lead to conditions such as hypertension, atherosclerosis, and heart failure. ...
A number of the emerging contaminants associated with having a harmful effect on the endocrine system have been recognized as endocrine disrupting chemicals. ...
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It has been well proven that endocrine-disrupting chemicals (EDCs) can accumulate in river sediments. ...
An assessment of the legal status of the substances with evidence or potential evidence of endocrine disrupting effects showed, that most of them are already subject to a ban or restriction or are addressed under existing Community legislation, although for reasons not necessarily related to endocrine disruption. ...
Endocrine disrupting compounds (EDCs) can impact the reproductive system by interfering with the hypothalamic‐pituitary‐gonadal (HPG) axis. While in vitro testing methods have been developed to screen chemicals for endocrine disruption, extrapolation of in vitro response to in vivo action shows inconsistent accuracy. ...
Phthalic acid esters are frequently detected in aquatic environment. In this study, zebrafish were exposed to low concentrations (0, 0.46, 4.0, and 37.5 µg/L) of mono‐(2‐ethylhexyl) phthalate (MEHP) for 81 days, and the effects on reproduction, gamete quality, plasma vitellogenin (VTG), sex steroids, and transcriptional profiles of key genes involved in steroidogenesis were investigated. The ...
Together, these gene expression alterations suggest the potential for BDE‐47 to disrupt endocrine signaling. There were no significant differences in plasma hormone levels, GSI, SCC or reproductive success. ...
Direct linkages between endocrine‐disrupting compounds (EDCs) from municipal and industrial wastewaters and impacts on wild fish assemblages are rare. ...
Little attention has focused on the effects of androgenic endocrine‐disrupting chemicals (EDCs) on amphibians. The present study aimed to investigate the effects of lower concentrations of the androgenic EDC 5α‐dihydrotestosterone (DHT) on gonadal differentiation and development in Pelophylax nigromaculatus, a true frog distributed widely in East Asia. ...
The chemical UV filter benzophenone‐3 (BP‐3) is suspected to be an endocrine disruptor based on results from in vitro and in vivo testing. However, studies including endpoints of endocrine adversity are lacking. The present study investigated the potential endocrine disrupting effects of BP‐3 in zebrafish (Danio rerio) in the ...
The highest exposures were in the Fen and Wei tributaries. Endocrine disruption risk from estrogens was predicted to be minimal in the main stem. ...
Interactions between insulin signaling and steroidogenesis suggest potential endocrine‐disrupting effects of metformin found in the aquatic environment. ...
As knowledge of contaminants capable of adversely modulating endocrine functions increases, attention is focused on the effects of synthetic progestins as environmental endocrine disrupters. ...
The environmental fate and transport of steroid growth promoters suggest potential for endocrine disrupting effects among ecological receptors; however, the initial excretion of steroid metabolites from cattle administered growth promoters has not been well characterized. ...
The aim of the present study was to investigate the effects of the androgenic endocrine disruptor 17β‐trenbolone on the sexual development of zebrafish (Danio rerio) with special emphasis on the question whether adverse outcomes of developmental exposure are reversible or persistent. An exposure scenario including a recovery phase was chosen to assess the potential reversibility of androgenic ...
PAHs and their metabolites have carcinogenic and endocrine disrupting effects in human and wildlife, and can have serious consequences. ...
Potential impacts on native fish species exposed to known endocrine disrupting chemicals such as atrazine, simazine and diuron have not been assessed. Here, we examine the endocrine and physiological effects of short‐term, acute exposure of environmentally relevant concentrations of analytical grade atrazine in juvenile barramundi (Lates ...
Our objective was to investigate the impact of Polybrominated diphenyl ethers (PBDEs) on fish reproduction over two generations. Zebrafish (Danio rerio) embryos (F0) were exposed to low concentrations (3, 10, 30 μg/L) of the PBDE mixture DE‐71 until they were sexually mature, and steroid hormone production, expression of genes involved in steroidogenesis, gonadal development and gamete ...
Mercury can disrupt the endocrine systems of mammals and fish, but little is known about its effects on avian hormones. ...
The pyrethroid insecticide, bifenthrin, is frequently detected at ng/L concentrations in tributaries of the San Francisco Bay Delta (SFBD). The estuary is also experiencing increasing salinity through climate change and water redirection. To evaluate the impacts of hypersaline conditions on bifenthrin toxicity in anadromous salmonids of the SFBD, a 14‐day laboratory exposure was performed ...