Endocrine System Articles & Analysis
15 articles found
These precise analytical methods support foundational understanding of endocrine systems. (2) Evaluate Experimental Interventions: In preclinical studies, steroid hormone profiling helps researchers assess the effects of potential therapeutic compounds on hormone pathways, providing crucial data before clinical ...
A number of the emerging contaminants associated with having a harmful effect on the endocrine system have been recognized as endocrine disrupting chemicals. ...
ByCoftec
Biochemical Pharmaceuticals As a biochemical enzyme preparation, it is widely used in clinical and scientific research, which can resist aging, anti-tumor, regulate the human endocrine system, and improve ...
The answer is that some PPCPs are known to disrupt the human endocrine system and can harm human health and the environment in other ways. ...
So, what are endocrine disruptors (ED)? They are chemicals that may interfere with the endocrine (hormonal) system and thereby produce harmful effects in both humans and wildlife. Hormones regulate the body's development, growth, reproduction, metabolism, immunity and behavior. Endocrine disruptors interfere with natural hormone ...
The US Environmental Protection Agency has responsibility for assessing endocrine activity of more than 10 000 chemicals, a task that cannot reasonably be achieved solely through use of available mammalian and nonmammalian in vivo screening assays. Hence, it has been proposed that chemicals be prioritized for in vivo testing using data from in vitro high‐throughput assays for ...
Endocrine disrupting compounds (EDCs) can impact the reproductive system by interfering with the hypothalamic‐pituitary‐gonadal (HPG) axis. ...
We used the zebrafish model to investigate the effects of long‐term TPP exposure on the endocrine system. For this purpose, we exposed zebrafish embryos to 5, 50 or 500 µg/L TPP for 120 d, and measured hormonal and transcriptional responses along the hypothalamus‐pituitary‐gonad (HPG), ‐interrenal (HPI), and ‐thyroid (HPT) axes. ...
This paper reports on short‐term fish reproduction assays in zebrafish and fathead minnow conducted to examine the potential for methyl tertiary butyl ether (MTBE) to cause effects on the endocrine system. Both studies were performed under Good Laboratory Practice and in accordance with OECD and USEPA test guidelines. ...
A modified tier 1 EDSP 21‐day fish short‐term reproduction assay (FSTRA) was used to evaluate the effects of sediment exposure from freshwater and brackish ponds in Bermuda on reproductive fecundity and endocrine function in fathead minnow (pimephales promelas) and killifish (fundulus heteroclitus). ...
The endocrine responses in male Murray rainbowfish (Melanotaenia fluviatilis) have been evaluated after exposures to biologically active concentrations of the non‐steroidal pharmaceutical, flutamide. ...
Mercury can disrupt the endocrine systems of mammals and fish, but little is known about its effects on avian hormones. ...
In the present study, we investigated the endocrine disrupting effects of di‐(2‐ethylhexyl)‐phthalate (DEHP), on the Chinese rare minnow (Gobiocypris rarus), an endemic fish distributing upstream waters in the Yangtze River. ...
The discussion also highlights the implications of the program for industry stakeholders. Concerns About Potential Endocrine Disruptors According to researchers, regulators, and other interested parties, a loosely defined class of substances referred to generally as “endocrine disruptors” are believed to interfere with the body’s endocrine ...
In areas where manure application is intensive, estrogens have been found in surface waters in concentrations known to affect the endocrine system of fish and amphibians. How the estrogens reach the surface waters is unclear. ...