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Gene Regulatory Network Articles & Analysis

4 articles found

Protein PPARd Can Induce Rapid Maturation of Human Pluripotent Stem Cell-Derived Cardiomyocytes

Protein PPARd Can Induce Rapid Maturation of Human Pluripotent Stem Cell-Derived Cardiomyocytes

Although peroxisome proliferator-activated receptor alpha (PPARa) signaling is most active in cardiac myocytes, these authors noted that PPARd signaling plays a separate and important role in effectively activating gene regulatory networks, increasing the number and distribution of organelles involved in energy production, and enhancing fatty ...

ByCreative BioMart


Genome Biology: Revealing the Genetic Structure of Seed Coat Content in Brassica Napus

Genome Biology: Revealing the Genetic Structure of Seed Coat Content in Brassica Napus

This study has made important progress in the analysis of the genetic basis of skin shell rate, new gene mining, and regulatory networks for seed carbon source allocation in B. napus. ...

ByLifeasible


CD Genomics Perspective: Using RNA Sequencing Technology to Study Ecology

CD Genomics Perspective: Using RNA Sequencing Technology to Study Ecology

For example, incorporating RNA-seq DE analysis with quantitative PCR (qPCR) and transcription factor binding site information allowed researchers to identify gene regulatory networks underlying the development of alternative jaw phenotypes in cichlid fish. Measurement of gene expression in wild populations and natural settings ...

ByCD Genomics


Exposure to a PBDE/OH‐BDE mixture alters juvenile zebrafish (Danio rerio) development

Exposure to a PBDE/OH‐BDE mixture alters juvenile zebrafish (Danio rerio) development

Fish were sampled at three time points and examined for developmental and skeletal morphology, apical thyroid and skeletal gene markers, and modifications in swimming behavior (as adults). Exposure to the high mixture resulted in > 85% mortality within one week of exposure, despite being below reported acute toxicity thresholds for individual congeners. ...

ByJohn Wiley & Sons, Ltd.

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