Immune Based Articles & Analysis
8 articles found
The proteins used in VLP formation are often derived from the virus itself, ensuring that the resulting particles present the same epitopes that can trigger an immune response. This feature is particularly advantageous in vaccine development, where the aim is to elicit an immune reaction without exposing individuals to pathogenic viruses. ...
Immunomodulatory therapies aim to enhance the immune system’s ability to recognize and eliminate viral pathogens. In 2024, the development of monoclonal antibodies and immune checkpoint inhibitors is at the forefront. These agents can be tailored to enhance the immune response specifically against viruses and are being tested in combination ...
Adjuvants, also known as immunomodulators or immune enhancers, are an additive to vaccines. Adjuvants are non-specific immune enhancers that enhance or alter the type of immune response to an antigen. ...
Attenuated vaccines have become one of the important development directions due to their potential advantages in terms of immune effects, for example, attenuated influenza vaccines can be inoculated by intranasal spray that is simpler, economical, painless, and consistent with the natural route of infection; they can retain the natural structure of all or most antigens of the ...
Pre-clinical in vivo data of the combination of AFM13 with PD1-blockade showed synergism and the potential for induction of cross-talk between innate and adaptive immunity.3 Based on these findings, we conducted a Phase 1b study evaluating the safety and tolerability of AFM13 in combination with pembrolizumab in patients with R/R Hodgkin ...
In recent years, immune-based cancer treatment methods have given doctors and patients a lot of hope. ...
But the most fundamental issue still seems to be that many proteins are not recognized by animal immune systems, which generate the polyclonal sera used as reagents in these assays. ...
These properties may lead to various physiological actions such as reducing cholesterol and attenuating blood glucose, maintaining gastrointestinal health, and positively affecting calcium bioavailability and immune function. Moreover, based on their physiochemical properties, many of the new sources of dietary fibre can help to improve the health benefits of new ...