Immunosuppression Articles & Analysis: This-Year
2 articles found
Research efforts now focus on designing next-generation inhibitors with improved selectivity, tissue penetration, and minimal immunosuppressive effects. In parallel, gene-editing strategies and siRNA therapeutics targeting mutant ELANE alleles are being explored for hereditary neutropenia syndromes. ...
The IP10-loaded platelets targeted and inhibited tumor cells in the B16F10 melanoma model and lessened immunosuppressive regulatory T cell activity through CD40L activation on platelet membranes which led to boosted anti-tumor immunity. ...