In Vitro Cytotoxicity Articles & Analysis
2 articles found
Abstract Purpose: To develop new therapies for children with solid tumors, we tested the cytotoxicity of natural killer (NK) cells expanded by coculture with K562-mb15-41BBL cells. We sought to identify the most sensitive tumor subtypes, clarify the molecular interactions regulating cytotoxicity, and determine NK antitumor potential in vivo. Experimental design: We tested in vitro ...
Based on the reports suggesting that exposures to low doses of ionising radiation may impede tumour development and/or trigger the activity of natural anti-neoplastic defence mechanisms we demonstrate in the present study that single whole-body irradiations of mice with 0.1 or 0.2 Gy X-rays significantly decreased the number of the induced tumour colonies in the lungs and that the effect was ...