In Vitro Method Articles & Analysis
4 articles found
The ability to design dsRNA specific to target genes has opened up new avenues for gene silencing technology. In Vitro Transcription One of the most common methods for producing dsRNA is in vitro transcription. ...
Assessing these properties during drug development can help identify suitable candidates and optimize formulations. The Importance of In Vitro Studies In vitro studies offer a controlled environment to assess drug permeability without the ethical and complexity concerns associated with in vivo studies. ...
Endocrine disrupting compounds (EDCs) can impact the reproductive system by interfering with the hypothalamic‐pituitary‐gonadal (HPG) axis. While in vitro testing methods have been developed to screen chemicals for endocrine disruption, extrapolation of in vitro response to in vivo action shows inconsistent accuracy. ...
Here, we evaluate the potential of a two‐compartment in vitro gastrointestinal tract model to compare the bioaccessibility of the antidepressant fluoxetine from invertebrate prey for birds and mammals. ...