In Vivo Evaluation Articles & Analysis
6 articles found
Posterolateral Rabbit Spinal Fusion Study I. Introduction Autologous bone has long been the gold standard for bone graft substitute in spinal fusion procedures. The limited supply and morbidity associated with using autologous graft material led to the development of alternative bone grafting materials. Bioactive glass has a long history of biomedical use and has been shown to facilitate mineral ...
In-vivo Evaluation Of A Novel Surgical Heart Valve Prosthesis Designed To Be Durable, Anticoagulant-free And Silent. ...
Due to a lack of robust in vivo gut models, animal studies are generally required to evaluate gut toxicity. ...
Our lead molecule exhibited no effect on the synthesis, processing, and secretion of PCSK9 either in the cells or into the media. In vivo pharmacological evaluation revealed that subcutaneous injection of 3 mg/kg of this antagonist resulted in a 25% reduction in LDL-C levels in mice fed a high fat/high cholesterol diet. ...
Nanoconjugates have matured from simple devices to multifunctional, biodegradable, non–toxic and non–immunogenic constructs, capable of delivering synergistically functioning drugs in vivo. The present study evaluates the efficacy of drug polymer self folding nano–conjugates of pectin–cisplatin to enhance blood circulating levels of cisplatin. ...
In this article, a premixed acidic CPC has been compared to a conventional water mixed brushite cement to evaluate whether the premixed concept affects the biological response. The cements were evaluated regarding the pH-variation in simulated body fluid (SBF). Further, the biocompatibility of the cement with human mesenchymal stem cells (MSC) was studied in ...