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Injection Techniques For Bulk Cell Articles & Analysis

11 articles found

VetStem Cell Therapy Helps Senior Lab Walk Again

VetStem Cell Therapy Helps Senior Lab Walk Again

We absolutely love hearing stem cell success stories from pet owners. But some stories are extra touching because it’s clear that VetStem really improved a pet’s quality of life. That’s the case with Molly, a senior chocolate lab who was suffering from severe osteoarthritis and a potential spinal ...

ByVetStem Biopharma


Injecting mRNA and generating CAR-T directly in the body to repair the heart in one shot

Injecting mRNA and generating CAR-T directly in the body to repair the heart in one shot

January 6, 2022—Researchers at the Perelman School of Medicine at the University of Pennsylvania published a research paper in Science titled: CAR-T cells produced in vivo to treat cardiac injury. Heart damage or inflammation can induce fibroblasts to overproduce fibrous material, causing cardiac fibrosis, which hardens the heart muscle and impairs heart function. Heart failure, liver ...

ByCreative Biolabs


Science: Knockout of this epigenetic gene gives CAR-T cells the ability to continuously attack cancer cells

Science: Knockout of this epigenetic gene gives CAR-T cells the ability to continuously attack cancer cells

Simply put, CAR-T is to transform the patient's immune T cells in vitro by biotechnology, so that they recognize antigens on the surface of tumor cells, and then inject these cells back into the patient to achieve the therapeutic effect of recognizing and killing cancer cells. In 2017, CAR-T therapy was first approved by the FDA for the treatment of blood cancers such as leukemia and lymphoma. ...

ByCreative BioMart


mRNA Delivery System

mRNA Delivery System

RNA is a hydrophilic, negatively charged macromolecule, and its ability to autonomously transmembrane is limited. Therefore, how to efficiently deliver mRNA to the cytoplasm and play a corresponding role is one of the key issues that limit the application of RNA therapy. The wide range of applications of therapeutic mRNA requires efficient and safe delivery methods. An ideal delivery system ...

ByBOC Sciences


Diabetic Patient Receives Stem Cell Therapy

Diabetic Patient Receives Stem Cell Therapy

In a pioneering “off-the-shelf ” drug treatment in place of a surgical procedure, Maruti Hospital on Tuesday inaugurated its Regenerative Medicine Department by administering stem cell therapy for a diabetic patient who lost four toes on both feet. Developed by pharma major, Cipla, in collaboration with Bengaluru-based, Stempeutics Research, over 14 years, it is available (on order) ...

ByStempeutics Research Pvt. Ltd.


Combatting the Opioid Crisis with Cell Therapies for Chronic Back Pain

Combatting the Opioid Crisis with Cell Therapies for Chronic Back Pain

It’s no secret that opioid addiction is at an all-time high and represents a major public health threat. The CDC estimates that opioid addiction resulted in a record 72,000 drug overdose deaths in 2017 alone. What strikes me as one of the most tragic parts of this narrative is that so many of these deaths were people who became addicted to opioids after simply seeking relief ...

ByDiscGenics, Inc.


Bisphenol S alters embryonic viability, development, gallbladder size, and mRNA expression in chicken embryos exposed via egg injection

Bisphenol S alters embryonic viability, development, gallbladder size, and mRNA expression in chicken embryos exposed via egg injection

Amid concerns about the toxicological effects and environmental prevalence of bisphenol A (BPA), efforts to find suitable, safer replacement alternatives are essential. Bisphenol S (BPS) is one potential chemical substitute for BPA; however, few studies are available confirming it has a more desirable ecotoxicological profile. In the present study, BPS was injected into the air cell of ...

ByJohn Wiley & Sons, Ltd.


Application of refractable nanocomposite on cell based therapy in central nervous system

Application of refractable nanocomposite on cell based therapy in central nervous system

Quantum Dots (QDs) are nano–particles carrying high stability fluorescence to follow the grafted cells which can be used in investigating the movement of cells and understanding the organogenesis of stem cells during development and wound repair processes in adulthood. For its easy acquirement and bypassing moral ethical issues, it makes the human adipose derived stem cells an attractive, ...

ByInderscience Publishers


Injection techniques for bulk cell seeding decellularised vascular scaffolds

Injection techniques for bulk cell seeding decellularised vascular scaffolds

Tissue engineering small diameter vascular grafts requires excessive culture times to produce an appropriate extracellular matrix (ECM). The use of decellularised exogenous tissue as a scaffold has the potential to overcome this limitation due to the preformed ideal ECM architecture that remains after decellularisation. While this scaffold reduces ECM maturation times cell seeding is difficult ...

ByInderscience Publishers


In vitro and in vivo evaluation of an injectable premixed calcium phosphate cement; cell viability and immunological response from rat

In vitro and in vivo evaluation of an injectable premixed calcium phosphate cement; cell viability and immunological response from rat

By using premixed calcium phosphate cement (CPC) the handling properties of the cement are drastically improved, which is a challenge for traditional injectable CPC. In this article, a premixed acidic CPC has been compared to a conventional water mixed brushite cement to evaluate whether the premixed concept affects the biological response. The cements were evaluated regarding the pH-variation in ...

ByInderscience Publishers


Inhibition of the development of pulmonary tumour nodules and stimulation of the activity of NK cells and macrophages in mice by single low doses of low-LET radiation

Inhibition of the development of pulmonary tumour nodules and stimulation of the activity of NK cells and macrophages in mice by single low doses of low-LET radiation

As indicated by a few recent reports, exposures to low doses of ionising radiation can trigger the activity of natural anti-tumour defence mechanisms and impede the development of transplantable tumours in rodents. In our experimental system, BALB/c mice were irradiated with a single dose of 0.1, 0.2, 0.5, or 1.0 Gy X-rays and then i.v. injected with L1 sarcoma cells. As shown by the results of ...

ByInderscience Publishers

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