Interferon Beta Articles & Analysis
9 articles found
Some of the primary classes include interleukins (IL), interferons (IFN), tumor necrosis factors (TNF), colony-stimulating factors (CSF), chemokines, and growth factors (GF). ...
Cytokine Classification Cytokines are categorized into various subtypes, including interleukins (IL), interferons (IFN), tumor necrosis factor (TNF), colony-stimulating factor (CSF), chemokines, and growth factors (GF). ...
Interleukin-2 (IL-2) is a 15kDa secretory protein with a 4-alpha-helical bundle structure. As a T-cell related growth factor, IL-2 can enhance the killing activity of NK cells and promote B cells to produce immunoglobulins. In addition, it aids in the development of regulatory T cells (Tregs), thereby producing peripheral T cell immune tolerance, as well as regulating the proliferation and ...
Unlike other mammalian cells, they do not secrete interferon alpha or beta when infected by viruses – this is one of the reasons that efficient replication of many viruses can be achieved in Vero cells, leading to high virus titers. ...
ByNuvonis
Adoptive cell transfer (ACT) therapy is one of the most effective therapeutic options for tumor immunotherapy that is currently emerging in clusters. Chimeric antigen receptors (CARs) and engineered T cell receptors (TCRs) are the main adoptive immunotherapies in recent years. TCR-engineered T cells express tumor antigen-specific receptors with alpha and beta chains generated from high-quality, ...
IL-1 consists of two genetically encoded peptide molecules, IL-1α and IL-1β, both with a molecular mass of about 17 ku, the former being secreted, while the latter is mostly cell bound. ...
More than 10 types of interferons have been identified and can be classified into alpha, beta and gamma (α, β and γ) types, which are subdivided into different subtypes. α and β interferons are mainly produced by virus-infected cells, while γ interferons are ...
Interferon (IFN) is an important mediator of innate and adaptive immunity. Interferons are generally composed of three types of cytokines: type I interferon family encoded by a variety of genes, mainly including a variety of interferon-α subtypes and interferon-β; type II ...
The SOLIDARITY trial will seek to repurpose currently available drugs, evaluating the experimental antiviral remdesivir, the malaria drugs chloroquine and hydroxychloroquine, a combination of the HIV drugs lopinavir and ritonavir, and lopinavir—ritonavir plus interferon beta. The trial will enrol anyone with confirmed COVID-19, with physicians inputting ...