Liver Tissue Articles & Analysis
24 articles found
At the core of S9 metabolic stability is the S9 fraction, which is a liver extract obtained from a homogenate of liver tissues, typically from certain rodent species. ...
Dysbiosis of the intestinal flora is associated with a variety of human metabolic diseases, such as obesity, diabetes mellitus, and nonalcoholic fatty liver disease. Regulation of lipoprotein metabolism by intestinal flora The intestine is not only a site of lipid digestion and absorption, but also a place where a large number of microorganisms reside. ...
AMPK can stop the metabolism of rapid tumor proliferation as well as restore the normal function of liver and other tissues in diabetic patients is a hot topic in disease research. ...
The results of the present study also suggest that the antioxidant effect of tetrahydrocurcumin may be related to the increase of oxidative stress. 3.Anti-fatty Liver Effect Pan Xuefeng et al. studied the anti-fatty liver effect of tetrahydrocurcumin on human liver cell line L02 induced by oleic acid in vitro and in vitro, and the results showed ...
Obesity is caused by excessive expansion of white adipose tissue. When nutrient intake is excessive, adipose tissue expands through either adipocyte hypertrophy or hyperplasia. ...
The larvae can invade lung, brain, liver, kidney and other tissues and organs, causing strongyloidiasis. ...
The mice were placed into two experimental groups: one that exercised on a treadmill for an hour in the early morning (early light) or evening (early dark), and one that did not. Following the exercise, tissues from various parts of the mice were collected, including serum, skeletal muscle, liver, epididymal white adipose tissue (eWAT), ...
This bipotential cell population can be isolated, expanded, and transplanted to repopulate the damaged liver soft tissue and differentiate into mature hepatocytes in order to restore liver function when endogenous regenerative mechanisms are exhausted. ...
The next great symbiotic relationship for humans could be between fabricated tissues and pond scum. Allevi Authors at Harvard Medical School and Brigham and Women’s Hospital recently published their findings on the use of algae in tissue engineering. ...
The liver plays an incredibly important role in the human body by metabolizing drugs and other compounds. ...
Nonalcoholic fatty liver disease (NAFLD) is associated with obesity but also found in non-obese individuals. ...
Publication Summary: The identification of targets and biomarkers and development of therapeutics for nonalcoholic fatty liver disease (NAFLD) may be accelerated by the use of well-characterized primary cell and tissue reagents, as well as improved in vitro human cell-based disease models, including three-dimensional (3D) bioprinted liver ...
The theory is simple, the body’s tissues need a specific intake of oxygen to function under normal conditions. When the body’s tissues are injured, the body needs supplemented levels of oxygen to activate its natural healing properties. ...
Publication Summary: The growing global incidence of NASH mirrors the availability of nutrients. Over-nutrition also results in insulin resistance and type-2 diabetes, which are often co-morbidities associated with NASH and are known to drive more adverse outcomes. MSDC-0602K, a modulator of the mitochondrial pyruvate carrier (MPC), is in clinical trials as a potential treatment for NASH. ...
Publication Summary: Nonalcoholic fatty liver disease (NAFLD) is a chronic condition that originates as lipid accumulation within hepatocytes (steatosis) and progresses into nonalcoholic steatohepatitis (NASH), characterized by lipid accumulation, inflammation, oxidative stress, and fibrosis. NAFLD is now recognized as the most common cause of chronic liver disease in the western world, with an ...
Publication Summary: Compound induced chronic liver injury can lead to initiation of profibrotic processes resulting in sustained production of growth factors and profibrotic cytokines where inflammation, tissue remodeling and repair pathways are activated simultaneously to counteract the injury. ...
Publication Summary: Nonalcoholic fatty liver disease (NAFLD) is a chronic condition that originates as lipid accumulation within hepatocytes (steatosis) and progresses into nonalcoholic steatohepatitis (NASH), characterized by lipid accumulation, inflammation, oxidative stress, and fibrosis. NAFLD is now recognized as the most common cause of chronic liver disease, with a prevalence of 25% ...
Publication Summary: Conventional cell therapy and tissue engineering approaches to treating liver diseases and injury are limited by low cell retention, poor engraftment, poor graft durability and complications including portal hypertension. ...
While in vitro testing methods have been developed to screen chemicals for endocrine disruption, extrapolation of in vitro response to in vivo action shows inconsistent accuracy. We describe here our tissue co‐culture of the fathead minnow (Pimephales promelas) HPG axis and liver (HPG‐L) as a tissue explant model that mimics in vivo results. ...
Mean [THg] and [TSe] of bearded seal liver and skeletal muscle tissues were used for intertissular comparison. ...