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Lung Cancer Articles & Analysis
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The biological functions of platelets are preserved in platelet micromotors with their ability to target cancer cells and pathogens. Biofuels enable motor-shaped platelet micromotors to achieve directed propulsion. ...
Smokers significantly increase the risk of developing Chronic Obstructive Pulmonary Disease (COPD) and lung cancer, as well as heart disease. The good news is quitting smoking brings immediate and long-term health benefits, reducing health risks and improving overall well-being. ...
Precision-Cut Lung Slices (PCLS) have emerged as a innovative ex vivo model that allows researchers to explore deep into lung physiology, disease mechanisms, and pharmacological responses. By offering a unique combination of biological complexity and controlled experimental conditions, PCLS serve as a critical bridge between the limitations of traditional in vitro cell cultures and the ...
ESMO updated its recommendations for NGS in advanced cancers this year, urging broader use of NGS in additional cancer types and the inclusion of tumor-agnostic biomarkers. The ESMO Precision Medicine Working Group (PMWG) first published its recommendations for when to use next-generation sequencing (NGS) in routine practice for patients with metastatic ...
Dr. Kate Sasser from Tempus led a discussion on the potential of antibody-drug conjugates (ADCs), their challenges in targeting tumor antigens, and the future of cancer treatment with Dr. Daniel Johnson, Dr. Funda Meric-Bernstam, and Dr. Kellogg Parsons. The oncology field is rapidly advancing with the development of antibody-drug conjugates (ADCs), offering new hope for ...
ByTempus
To begin with, SN38-BSA is composed of SN38, a potent anti-cancer drug, and BSA or Bovine Serum Albumin. SN38 is the active metabolite of the prodrug irinotecan, commonly used in chemotherapy. It's known for its high potency against cancer cells but has limitations in terms of bioavailability and solubility. ...
The two antigen-binding arms respectively bind to two antigens on the surface of cancer cells, which can effectively enhance the binding specificity and targeting of the antibody to cancer cells and reduce side effects such as off-target. ...
How is nano-flow cytometry being used to improve early disease detection? Cancer detection: Nano-flow cytometry is being used by researchers to create new blood tests that can identify cancer cells in their earliest stages. As an illustration, scientists at the University of California, Los Angeles have created a brand-new blood test that can find circulating ...
It is currently undergoing multiple clinical trials and is used alone or in combination to treat metastatic triple-negative breast cancer (first-line or adjuvant treatment), metastatic breast cancer, non-small cell lung cancer, metastatic Urothelial carcinoma, metastatic castration-resistant prostate cancer, and ...
In addition to causing degradation of the target protein HER2, SignalTAC also downregulates downstream signaling (PI3K/AKT/mTOR) and promotes apoptosis and inhibits the proliferation of HER2-driven cancer cells. Cytokine Receptor-Targeting Chimeras (KineTACs) Due to limitations in lysosome delivery targeting chimeras, such as low modularity, high development difficulty, poor ...
By inhibiting this enzyme, camptothecin prevents cancer cells from dividing and can induce cell death. Several derivatives of camptothecin, such as irinotecan and topotecan, have been developed and approved for the treatment of various cancers, including colorectal, lung, and ovarian cancers. ...
However, understanding the roles of CADM molecules in tumor immune escape may offer valuable insights for developing novel immunotherapeutic strategies to overcome immune evasion and enhance the body's ability to recognize and eliminate cancer cells. CADM1 and Lung Cancer CADM1 is often downregulated or lost in lung ...
Therefore, quantum dot-labeled microspheres can be used for multiplex detection of miRNA overexpression in human lung cancer cells. Fluorescent Microspheres for Protein Detection Multi-color quantum dot-bound microspheres have been widely proven to be used for the simultaneous detection of multiple antigens, including IgG, tumor markers, and pathogenic markers. ...
Introduction Genomics has revolutionized cancer research, transforming the way we diagnose, treat, and monitor cancer. ...
Microbial Amplicon Sequencing Analysis of Microbial Populations The risk of lung cancer is known to be associated with exposure to cigarette smoke carcinogens and alterations in intestinal microbiota. However, the impact of NNK and BaP—two crucial components of cigarette smoke carcinogens—on the intestinal microbiota of lung ...
In recent years, further research on MMP-3 has revealed its association with conditions such as glioma, ocular tumors, breast cancer, gastric cancer, non-small cell lung cancer, liver cancer, and even COVID-19. ...
Enfortumab vedotin-ejfv (PADCEV®) is a first-in-class antibody-drug conjugate (ADC) that targets Nectin-4, a cell surface protein highly expressed in bladder cancer. Preclinical data suggest that the anticancer activity of Enfortumab Vedotin is attributed to its binding to cells expressing Nectin-4, followed by internalization and release of the anti-tumor agent monomethyl ...
According to the latest data, breast cancer has overtaken lung cancer to become the most common cancer among women, and the death rate is the second highest among female tumors, seriously affecting the physical and mental health of women around the world. ...
All the news collected help reader of report to understand the gaps in the marketplace and competitor’s strength and weakness thereby, providing insights to enhance product and service.Global Paclitaxel Injection Industry Segmentation:By ApplicationProstate Cancer Breast Cancer Non-Small Cell Lung Cancer AIDS related Kaposi's ...
BioMark Diagnostics Inc. is a Canadian-based cancer diagnostic company with head office located in Richmond, British Columbia and operating lab in Quebec City, Quebec. ...