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Lung Fibrosis By Regulating Epithelial Articles & Analysis

4 articles found

Fabrication And Characterization Of 3D Bioprinted Triple-Layered Human Alveolar Lung Models

Fabrication And Characterization Of 3D Bioprinted Triple-Layered Human Alveolar Lung Models

Researchers from Nanyang Technological University and its Center for 3D printing (SC3DP) have developed a 3D printed a highly repeatable and scalable three-dimensional in-vitro alveolar lung model using our REGENHU bioprinter, that could be exploited for pathogen translocation studies and respiratory-related toxicological testing applications. The triple-cell layered lung model was realized ...

ByRegenhu


Electronic cigarettes disrupt lung lipid homeostasis and innate immunity independent of nicotine

Electronic cigarettes disrupt lung lipid homeostasis and innate immunity independent of nicotine

Abstract Electronic nicotine delivery systems (ENDS) or e-cigarettes have emerged as a popular recreational tool among adolescents and adults. Although the use of ENDS is often promoted as a safer alternative to conventional cigarettes, few comprehensive studies have assessed the long-term effects of vaporized nicotine and its associated solvents, propylene glycol (PG) and vegetable glycerin ...

ByJohnson Controls, Inc.


Syndecan-1 promotes lung fibrosis by regulating epithelial reprogramming through extracellular vesicles

Syndecan-1 promotes lung fibrosis by regulating epithelial reprogramming through extracellular vesicles

Idiopathic pulmonary fibrosis (IPF) is a chronic and fatal lung disease. A maladaptive epithelium due to chronic injury is a prominent feature and contributor to pathogenic cellular communication in IPF. Recent data highlight the concept of a “reprogrammed” lung epithelium as critical in the development of lung ...

ByJohnson Controls, Inc.


Nanomechanics of lung epithelial cells

Nanomechanics of lung epithelial cells

Nanobiotechnology provides powerful tools for manipulating cells with nanometric resolution and with simultaneous measurement of force with pN resolution. We review the application of atomic force microscopy (AFM) and magnetic tweezers for probing cell nanomechanics. AFM measures the mechanical properties of the cell by indenting its surface by means of a flexible cantilever with a sharp tip at ...

ByInderscience Publishers

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