Metabolic Changes Articles & Analysis
13 articles found
Automation and real-time monitoring systems enhance the efficiency of the manufacturing process, allowing for precise adjustments in response to metabolic changes in the cell culture. Quality Assurance in Antibody Production Ensuring the quality and consistency of the produced antibodies is paramount. ...
Investigations into the mechanisms of podocyte injury are ongoing, with a focus on understanding how factors like inflammation, oxidative stress, and metabolic changes contribute to podocyte damage. By elucidating these pathways, researchers hope to identify potential therapeutic targets to prevent or reverse kidney damage. ...
Various factors contribute to this phenomenon, including genetic mutations, alterations in drug targets, enhanced drug efflux, and changes in metabolic pathways. In cancer, the heterogeneity of tumors often results in a subset of cells that can survive initial treatments, leading to relapse and metastasis. ...
SpectroscopyEvaluate the efficiency of oxidative phosphorylation by measuring the change in absorption or fluorescence spectra of certain components in the mitochondrial respiratory chain.2. ...
Many abnormal physiological states are associated with disorders of lipid metabolism. Studying the changes of lipids in different states of the organism at the systemic level can help analyze the mechanisms of lipid metabolic networks. ...
Metabolomics studies the endogenous metabolic activities of life under the influence of the internal and external environments, including the detection and analysis of metabolite types and quantities and their change patterns, thus studying the nature of the occurrence and development of collective life activities. ...
Case Study Description Warming Waters and Metabolic Rates As climate change continues to warm our world and its waters, scientists and researchers across the globe have spent years attempting to understand and predict the ramifications such warming will have on Earth’s ecosystems. ...
Pancreatic cancer is a highly malignant digestive system tumor, and the five-year survival rate of patients after diagnosis is only about 10%. Changes in metabolism are one of the important features of tumor cells. Tumor cells undergo metabolic reprogramming to generate the substances, energy, and redox forces required for their rapid ...
These authors investigated multiple metabolic modifications of hPSC-CMs. They also determined the role of a metabolic switch from glycolysis to fatty acid oxidation in hPSC-CMs generated in the laboratory by protein induction called peroxisome proliferator activated receptor delta (PPARd). This metabolic switch is a critical part of the heart ...
I didn’t want to heat the local tissue in this case, but I did want to create metabolic changes at the cellular level to speed healing. As I performed my manual lymphatic drainage techniques, I did use the diathermic effect of the capacitive electrode to dilate lymph vessels and vascular tissue proximal to the injury so that fluid drained from the surgical ...
These results highlight a neddylation-dependent mechanism regulating gene expression in the liver that is disrupted in early metabolic liver disease and may contribute to the progression to NASH, cirrhosis, and ultimately hepatocellular carcinoma. ...
A sequencing batch reactor was used to investigate the effect of carbon sources on the metabolism of activated sludge. Acetate and phenol, with the chemical oxygen demand (COD) of 330–350 mg L−1, was used as the carbon source in Periods I and II, respectively. Acetate decreased in the initial 120 min with the intracellular storage materials (XSTO), extracellular polymeric substances (EPS), ...
Δ6-desaturase is a membrane bound enzyme located in a pivotal position within the Essential Fatty Acid metabolic pathway. Changes in the activity of Δ6-desaturase affect the cellular provision of long chain polyunsaturated fatty acids and therefore factors that influence this enzyme are considered relevant to disease processes. ...