Metabolic Flux Articles & Analysis
4 articles found
Biosynthesis: Intermediates of the TCA Cycle serve as precursors for the biosynthesis of amino acids, heme, and other essential biomolecules. Metabolic Flexibility: The cycle can integrate inputs from various metabolic pathways, allowing cells to adapt to changing nutritional states. ...
One essential approach to studying cellular metabolism is Metabolic Flux Analysis (MFA), a powerful tool that reveals the intracellular activities and metabolic dynamics of living systems. ...
Her team's imaging shows how the metabolism of the mouse brain changes when glycolysis is blocked in neurons. "This neuroimaging approach provides unprecedented information on brain metabolism," Chaumeil said. "The promise of metabolic imaging to inform basic biology and improve clinical care is enormous; there is still much to be explored." ...
In order to gain a better quantitative understanding of the factors controlling the metabolic transition, the fermentation dynamics was investigated for a temperature-sensitive strain cultivated in batch and glucose-limited continuous cultures. For non-excreting cells at 33°C, increasing the growth rate resulted in strong increases in the central metabolic ...