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Microbiome Research Articles & Analysis

18 articles found

Best Practices for Bioinformatics Analysis of 16S rRNA Sequencing via NGS

Best Practices for Bioinformatics Analysis of 16S rRNA Sequencing via NGS

The advent of next-generation sequencing (NGS) has revolutionized the field of microbiome research, particularly through the analysis of 16S rRNA gene sequencing. ...

ByCD Genomics


What Is Microbiome and How to Study It

What Is Microbiome and How to Study It

The term microbiome comes from the Greek word micro which means small and bios meaning life. It is defined as "a characteristic microbial community occupying a reasonable well-defined habitat which has distinct physiochemical properties". Many researchers in the past defined microbiome based on different contexts such as ecological and genetic ...

ByCD Genomics


Overview of Metatranscriptomic Sequencing: Principles, Workflow, and Applications

Overview of Metatranscriptomic Sequencing: Principles, Workflow, and Applications

What is metatranscriptomic sequencing? Metatranscriptomic sequencing provides direct access to culturable and non-culturable microbial transcriptome information by large-scale, high-throughput sequencing of transcripts from all microbial communities in specific environmental samples. Metatranscriptomic sequencing offers an opportunity to randomly sequence mRNAs as a unit for understanding the ...

ByCD Genomics


Plant-based cures for Vector-borne disease

Plant-based cures for Vector-borne disease

Scientists have used these intricate digital databases to research target molecular matches between diseases and cures. Researchers also look at targets for treatments of disease and try to design molecules to fit. An example of a research target would be Borrelia burgdorferi, the principal bacteria that causes Lyme disease. ...

ByGalaxy Diagnostics, Inc.


The Relationship Between the Gut Microbiome and Drugs Is Greater Than We Thought

The Relationship Between the Gut Microbiome and Drugs Is Greater Than We Thought

Drugs may affect host metabolism or clinical efficacy by positively and negatively modulating the gut microbiome. Not only antibiotics medicines, but also other commonly used drugs have been shown to affect the gut microbiome in population-based studies. ...

ByCD Genomics


How does your Vaginal Microbiome Affect your Cancer Risk?

How does your Vaginal Microbiome Affect your Cancer Risk?

When you hear about the vaginal microbiome (VMB), your first thought may be the role it plays in stuff like yeast infections or bacterial vaginosis (BV). ...

ByJuno Bio


Preterm Birth and the Vaginal Microbiome

Preterm Birth and the Vaginal Microbiome

But it’s not just about you - your vaginal microbiome (VMB) can also impact the outcome of your pregnancy and the health of your baby. ‍When it comes to the VMB’s impact on pregnancy, research has so far told us a few key things: Increased levels of some kinds of bacteria + decreased levels of other kinds of bacteria = increased risk of ...

ByJuno Bio


CP101, an Investigational Oral Microbiome Therapeutic for the Prevention of Recurrent C. difficile Infection

CP101, an Investigational Oral Microbiome Therapeutic for the Prevention of Recurrent C. difficile Infection

Background: Disruption of the microbiome is key to the pathogenesis of recurrent Clostridioides difficile infection (CDI). Place bo-control led trials assessing microbiome therapeutics have demonstrated efficacy in recurrent CDI; hov/ever, long-term safety and efficacy data from rigorously conducted studies of microbiome therapies, including cumulative efficacy in those who received a second dose ...

ByFinch Therapeutics Group, Inc.


CD Genomics Perspective: High-Throughput Sequencing Approach to Explore the Human Microbiome

CD Genomics Perspective: High-Throughput Sequencing Approach to Explore the Human Microbiome

The Use of Microbiome Sequencing in Cancer Research A growing body of evidence now suggests that human microbial dysbiosis has a crucial role in cancer development and progression. ...

ByCD Genomics


Introduction to Microbiomics

Introduction to Microbiomics

Microbiomics is the study of the microbiome, which explores their structure, function, and relationship with the environment or the host. Microbiome research can be broadly divided into three stages: 1) The first stage: Before the 1970s, strains were obtained mainly by traditional microbial isolation and culture ...

ByCreative Proteomics


Metabolomics in Gut Microbiota Research

Metabolomics in Gut Microbiota Research

With rapid development in sequencing technology, researchers can better assess the effect of the gut microbiome on human health. ...

ByCreative Proteomics


Amplicon Sequencing for Microbiome Research: Introduction, Advantages, and Applications

Amplicon Sequencing for Microbiome Research: Introduction, Advantages, and Applications

Profiling microbial communities and microbiomes are beneficial in understanding key processes happening in the environment. ...

ByCD Genomics


Human Microbiome Research Promotes Progress of Precision Medicine

Human Microbiome Research Promotes Progress of Precision Medicine

Over the past few years, human microbiome research, defined as the research of the whole DNA component of micro-organisms that reside in our bodies, has grown quickly. ...

ByCD Genomics


Introduction to Microbiomics

Introduction to Microbiomics

Microbiomics is the study of the microbiome, which explores their structure, function, and relationship with the environment or the host. Microbiome research can be broadly divided into three stages: 1) The first stage: Before the 1970s, strains were obtained mainly by traditional microbial isolation and culture techniques, ...

ByCreative Proteomics


Accurately Recapitulating Environmental Niches in  Vitro Models of the Intestine

Accurately Recapitulating Environmental Niches in Vitro Models of the Intestine

Availability of such models is key to progress in compound screening, disease modeling, and microbiome research. Defining a Niche A niche is a multidimensional space of resources and conditions that define where an organism can survive and grow. ...

ByAltis Biosystems


Distinct signatures of gut microbiome and metabolites associated with significant fibrosis in non-obese NAFLD

Distinct signatures of gut microbiome and metabolites associated with significant fibrosis in non-obese NAFLD

These results indicate that fibrosis severity rather than necroinflammatory activity is more likely associated with the changes of gut microbiome and underlying BMI status may also be an important factor responsible for alterations of the gut microbiome. ...

ByKoBioLabs


Symberix Featured in PNAS

Symberix Featured in PNAS

"Using a combination of chemistry and genomics, researchers are now beginning to identify these mechanisms. As they do, they’re uncovering ways to inhibit the microbial enzymes that cause distressing side effects. ...

BySymberix, Inc.


Symberix Featured in Nature

Symberix Featured in Nature

Durham, NC (February 3, 2020) - An article in Nature highlights Symberix's efforts to understand the complex relationship between drugs and the microbiome. The paper discusses recent contributions to the emerging field of “pharmacomicrobiomics” -- the study of how microbes impact drug disposition, efficacy, and toxicity. ...

BySymberix, Inc.

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