Microbiome Research Articles & Analysis
18 articles found
The advent of next-generation sequencing (NGS) has revolutionized the field of microbiome research, particularly through the analysis of 16S rRNA gene sequencing. ...
The term microbiome comes from the Greek word micro which means small and bios meaning life. It is defined as "a characteristic microbial community occupying a reasonable well-defined habitat which has distinct physiochemical properties". Many researchers in the past defined microbiome based on different contexts such as ecological and genetic ...
What is metatranscriptomic sequencing? Metatranscriptomic sequencing provides direct access to culturable and non-culturable microbial transcriptome information by large-scale, high-throughput sequencing of transcripts from all microbial communities in specific environmental samples. Metatranscriptomic sequencing offers an opportunity to randomly sequence mRNAs as a unit for understanding the ...
Scientists have used these intricate digital databases to research target molecular matches between diseases and cures. Researchers also look at targets for treatments of disease and try to design molecules to fit. An example of a research target would be Borrelia burgdorferi, the principal bacteria that causes Lyme disease. ...
Drugs may affect host metabolism or clinical efficacy by positively and negatively modulating the gut microbiome. Not only antibiotics medicines, but also other commonly used drugs have been shown to affect the gut microbiome in population-based studies. ...
When you hear about the vaginal microbiome (VMB), your first thought may be the role it plays in stuff like yeast infections or bacterial vaginosis (BV). ...
ByJuno Bio
But it’s not just about you - your vaginal microbiome (VMB) can also impact the outcome of your pregnancy and the health of your baby. When it comes to the VMB’s impact on pregnancy, research has so far told us a few key things: Increased levels of some kinds of bacteria + decreased levels of other kinds of bacteria = increased risk of ...
ByJuno Bio
Background: Disruption of the microbiome is key to the pathogenesis of recurrent Clostridioides difficile infection (CDI). Place bo-control led trials assessing microbiome therapeutics have demonstrated efficacy in recurrent CDI; hov/ever, long-term safety and efficacy data from rigorously conducted studies of microbiome therapies, including cumulative efficacy in those who received a second dose ...
The Use of Microbiome Sequencing in Cancer Research A growing body of evidence now suggests that human microbial dysbiosis has a crucial role in cancer development and progression. ...
Microbiomics is the study of the microbiome, which explores their structure, function, and relationship with the environment or the host. Microbiome research can be broadly divided into three stages: 1) The first stage: Before the 1970s, strains were obtained mainly by traditional microbial isolation and culture ...
With rapid development in sequencing technology, researchers can better assess the effect of the gut microbiome on human health. ...
Profiling microbial communities and microbiomes are beneficial in understanding key processes happening in the environment. ...
Over the past few years, human microbiome research, defined as the research of the whole DNA component of micro-organisms that reside in our bodies, has grown quickly. ...
Microbiomics is the study of the microbiome, which explores their structure, function, and relationship with the environment or the host. Microbiome research can be broadly divided into three stages: 1) The first stage: Before the 1970s, strains were obtained mainly by traditional microbial isolation and culture techniques, ...
Availability of such models is key to progress in compound screening, disease modeling, and microbiome research. Defining a Niche A niche is a multidimensional space of resources and conditions that define where an organism can survive and grow. ...
These results indicate that fibrosis severity rather than necroinflammatory activity is more likely associated with the changes of gut microbiome and underlying BMI status may also be an important factor responsible for alterations of the gut microbiome. ...
"Using a combination of chemistry and genomics, researchers are now beginning to identify these mechanisms. As they do, they’re uncovering ways to inhibit the microbial enzymes that cause distressing side effects. ...
Durham, NC (February 3, 2020) - An article in Nature highlights Symberix's efforts to understand the complex relationship between drugs and the microbiome. The paper discusses recent contributions to the emerging field of “pharmacomicrobiomics” -- the study of how microbes impact drug disposition, efficacy, and toxicity. ...