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Microrna Articles & Analysis
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Furthermore, exosomes also carry small RNAs, such as microRNAs, which influence gene expression and can modulate metabolic pathways in recipient cells. ...
This method is particularly valuable for identifying the target genes regulated by microRNAs (miRNAs), which are small, endogenous non-coding RNAs approximately 22 nucleotides in length. miRNAs play crucial roles in various biological processes, including cell proliferation, apoptosis, differentiation, metabolism, and responses to environmental stresses such as drought and high ...
MicroRNAs (miRNAs) are small, non-coding RNA molecules that play a crucial role in the regulation of gene expression. ...
The retained intron can contain important regulatory elements, such as protein-binding sites or microRNA target sites, which can influence gene expression or protein function. ...
MicroRNAs (miRNAs) are a type of small single-stranded non-coding RNA molecules of 18 ~ 24 nucleotide (nt) in length. ...
Controlling the Immune Suppressor: Transcription Factors and MicroRNAs Regulating CD73/NT5E. Front Immunol. 2018 Apr 18;9:813. doi: 10.3389/fimmu.2018.00813. ...
The retained intron can contain important regulatory elements, such as protein-binding sites or microRNA target sites, which can influence gene expression or protein function. ...
Small RNAs are important functional molecules in organisms, which have three main categories: microRNA (miRNA), small interfering RNA (siRNA), and piwi-interacting RNA (piRNA). ...
• Small RNA profiling Small RNA species usually include microRNA (miRNA), small interfering RNA (siRNA), and piwi-interacting RNA (piRNA), as well as other types of small RNA, such as small nucleolar RNA (snoRNA) and small nuclear RNA (snRNA). ...
Some circRNAs can interact with microRNAs, regulate translation processes and participate in the terms of immune responses. ...
RNA-seq promised unprecedented sensitivity for sensing the expression differences among rare transcripts, splice variants, and microRNAs, then quickly surpassing microarrays as the high-throughput method for studying differential expression in non-model species. ...
Accumulating evidence suggests that multiple growth factors and cytokines induce mcl1 gene expression, multiple microRNAs and lncRNAs control the stability of mcl1 mRNA, and mTORC1 promotes the translation of mcl1 protein. ...
Importantly, we demonstrate that syndecan-1 controls the packaging of several antifibrotic microRNAs into EVs that have broad effects over several fibrogenic signaling networks as a mechanism of regulating epithelial plasticity and pulmonary fibrosis. ...
Tobacco can easily accumulate certain heavy metals in leaves and thus poses a potential threat to human health. To systematically dissect Cr-responsive miRNAs and their targets at the global level, four small RNA libraries were constructed from the roots of Cr-treated (Cr) and Cr-free (control) two contrasting tobacco genotypes,Yunyan2 (Cr-sensitive) and Guiyan1 (Cr-tolerant). Using ...
While a number of protein-encoding genes are known to be involved in this process, information on the role of microRNAs (miRNAs) in TGF-β-induced cell migration and invasion is still limited. ...
We found that the 3'UTR is >1,500 bp longer in parental cells and, using the miRBase TARGETs database, identified a putative microRNA (miRNA) binding site, distinct from the recently reported hsa-miR520h site, in the portion of the 3'UTR missing from ABCG2 mRNA in the resistant cells. ...
Substantial data indicate that microRNA 21 (miR-21) is significantly elevated in glioblastoma (GBM) and in many other tumors of various origins. This microRNA has been implicated in various aspects of carcinogenesis, including cellular proliferation, apoptosis, and migration. ...
The PicTar program predicted that microRNA-126 (miR-126), miR-145, and let-7s target highly conserved sites within the Hoxa9 homeobox. There are increased nucleotide constraints in the three microRNA seed sites among Hoxa9 genes beyond that required to maintain protein identity, suggesting additional functional conservation. In preliminary experiments, forced ...
microRNAs (miRNAs) are abundant, [1]21-nucleotide, noncoding regulatory RNAs. ...
Recent research has identified critical roles for microRNAs in a large number of cellular processes, including tumorigenic transformation. ...