Microvascular Articles & Analysis
15 articles found
Skeletal muscle microvascular endothelial cells (SMECs) play an essential role in maintaining muscle function, metabolism, and overall health. ...
FGL2 and disease Studies have found that FGL2 is highly expressed in microvascular endothelial cells, causing microcirculatory disturbance, promoting myocardial and liver ischemia-reperfusion injury, arthritis, type 2 diabetic heart failure, and type 2 diabetic nephropathy; FGL2 is highly expressed in inflammatory bowel disease mucosa , correlated with disease severity; in HCV, ...
Endothelial cells, for example, are present in both HFpEF and HFrEF as shown by a similar loss in cardiac microvascular density. [4] This, however, is where the similarities end. Contrasting comorbidities in HFpEF and HFrEF can affect endothelial function in different ways, with microvascular complications being more prevalent in HFpEF than in HFrEF [4]. ...
Comorbidities have a cumulative and synergistic effect on cardiac function and outcomes. [11] The elderly with HFpEF have 5.5 noncardiac comorbidities on average. [12] Aging promotes coronary microvascular endothelial abnormalities, myocardial remodeling, and dysfunction in HFpEF [13,14,15]. ...
Introduction Neurologic complications are frequently reported in COVID-19, but our understanding of their pathophysiologic causes and neuroanatomical correlates is limited. While several structural brain imaging findings have been reported in COVID-19, including non-spherical signal abnormalities on Susceptibility-Weighted Imaging (SWI), conventional perfusion imaging has not provided consistent ...
The heart is a unique organ in many respects since its activity is mandatory to sustain life. The heart’s circulatory system and coronary flow regulation are highly adapted to the vital role of the heart in sustaining life and to everyday physiological challenges. Understanding coronary physiology is key for treating patients with ischemic heart disease in general, and ...
When implanted as end-to-end abdominal aorta grafts in nude rats, BVPs were able to restore near-normoglycemia durably for 90 days and developed robust microvascular infiltration from the host. Furthermore, pilot implantations in pigs were performed, which demonstrated the scalability of the technology. ...
Vitamin P (Bioflavonoids): strengthens microvascular tissues, prevents and treats bleeding gums, enhances the effectiveness of vitamin C, strengthens the body's resistance to bacterial infections, and treats edema and dizziness caused by inner ear diseases. ...
It detects any changes within the blood volume in the microvascular tissues which is similar to how conventional pulse oximeters work. ...
BySky Labs
Another application in clinical practice, is the routine use of PPG to monitor cardiac-induced blood volume changes in microvascular beds at peripheral body sites. PPG is regarded as an effective low-cost technology that can be applied to various aspects of cardiovascular monitoring. ...
BySky Labs
By combining different cell populations in a fibrin bioink, researchers from Trinity College Dublin, Royal College of Surgeons in Ireland and University of Illinois Chicago were able to sprout an in vitro microvessel network that was then exploited to prevascularise a 3D printed scaffold implanted in a critical size femoral defect using REGENHU bioprinter. This dual approach was observed to ...
ByRegenhu
Highlights Deterministic barcoding in tissue enables NGS-based spatial multi-omics mapping DBiT-seq identified spatial patterning of major tissue types in mouse embryos Revealed retinal pigmented epithelium and microvascular endothelium at cellular level Direct integration with scRNA-seq data allows for rapid cell type identification Summary We ...
Neoplasia is the abnormal growth and proliferation of abnormal cells or abnormal amounts of cells due to a benign or malignant process. There can be benign tumors, or neoplasms, and malignant ones. Remember that it's the malignant tumors, or cancer, that can metastasize, which is when cancer spreads around the body. Leukemia is used for lymphoid neoplasms presenting with widespread involvement ...
We show how microfluidics technology can be used to fabricate simple and innovative biomimetic tools to shed new light on physiopathological events occurring in the blood microcirculation. Examples of applications are given in the context of the acute respiratory distress syndrome (ARDS), an inflammatory disease of the lung triggered by a massive arrest of white blood cells in the lung ...
It is now accepted that during the early stages of development of coronary and carotid atherosclerotic plaques, activation of vasa vasorum (VV) at specific sites in the adventitia initiates their proliferation or 'angiogenesis', and migration through the media into the intima of unstable developing lesions. Plaques regions containing these immature vessels tend to exhibit increased inflammation ...