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Oral Activated Articles & Analysis

2 articles found

Abstract 10306: Identification and Characterization of Orally Bioavailable Small Molecule Protease Proprotein Convertase Subtilisin-like Kexin Type 9 Inhibitors (Best of Basic Science Abstract)

Abstract 10306: Identification and Characterization of Orally Bioavailable Small Molecule Protease Proprotein Convertase Subtilisin-like Kexin Type 9 Inhibitors (Best of Basic Science Abstract)

We have identified inhibitors of the autocatalytic processing by virtual docking of millions of commercial compounds into the atomic structure of the PCSK9 active site. Top scoring compounds that showed the best fit in the active site were selected for screening. ...

ByShifa Biomedical Corporation


Structural model of polymeric nanospheres containing indomethacin ethyl ester and in vivo antiedematogenic activity

Structural model of polymeric nanospheres containing indomethacin ethyl ester and in vivo antiedematogenic activity

The indomethacin ethyl ester that is insoluble in water and presents in vitro anti-inflammatory activity was encapsulated in the nanospheres. Furthermore, the antiedematogenic activity has been studied in rats. ...

ByInderscience Publishers

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