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Particle Size Distribution Articles & Analysis

9 articles found

How to Detect the Thermal Stability of Collagen Protein?

How to Detect the Thermal Stability of Collagen Protein?

Dynamic Light Scattering (DLS)(1) PrincipleDLS measures the rate of particle movement in solution, thereby inferring the distribution of particle sizes, and can be used to monitor changes in the aggregation state of proteins.(2) OperationMeasure the DLS data of the collagen solution at different temperatures. As the temperature ...

ByMtoZ Biolabs


How to Prepare Drug Microcapsules: A Holistic Approach

How to Prepare Drug Microcapsules: A Holistic Approach

It is a crucial parameter that directly impacts the therapeutic efficacy of the drug delivery system. Particle size distribution is another vital parameter that determines the physical characteristics of the microcapsules. A narrow particle size distribution ensures uniformity, which is essential ...

ByCD Formulation


How to Select Pharmaceutical Excipients?

How to Select Pharmaceutical Excipients?

Changes in the excipient’s physical and chemical properties may affect the quality of the preparation in terms of viscosity, particle size and distribution, fluidity, moisture, pH, etc. For the polymer materials used in sustained and controlled release formulations, changes in molecular weight and viscosity may have a significant impact on ...

ByCD Formulation


MSD Wellcome Trust Hilleman Laboratories, India - Case Study

MSD Wellcome Trust Hilleman Laboratories, India - Case Study

The process of spray drying makes particle engineering more feasible; by manipulating the conditions of the spray-drying process, it is possible to adjust various particle properties such as size distribution, dispersibility, and surface enrichment of biopharmaceuticals. ...

ByBUCHI


Air Quality in Operating Rooms and Surgical Suites

Air Quality in Operating Rooms and Surgical Suites

For operating rooms, that is Category 4 which is 10,000 particle/M3 of 0.1 microns or larger (Table ISO 14644-1). (Note: the ISO 14644 Standard has replaced Federal Standard 209E). In any event, airborne particles can be measured in real time using direct reading particle counters that can also measure particle ...

ByPHASE Associates, LLC


Biomedical applications of iron oxide nanostructures

Biomedical applications of iron oxide nanostructures

All these biomedical and bioengineering applications require that these nanostructures have high magnetisation values and size smaller then 100 nm with overall narrow particle size distribution. ...

ByInderscience Publishers


The development of nanoparticulate materials for biodegradable bone fracture plates: (I)

The development of nanoparticulate materials for biodegradable bone fracture plates: (I)

A cost effective route for the production of nanoparticulate calcium carbonate with high phase purity, a narrow particle size range and low tendency for agglomeration represents a crucial stage in the development of degradable nanocomposite materials for the manufacture of fracture fixation plates. In this study, the size, morphology and zeta ...

ByInderscience Publishers


Micro Flow Imaging Technology for Parenteral Applications

Micro Flow Imaging Technology for Parenteral Applications

MFI™ for Parenteral Drugs USP Chapter 788 (Particulate Matter in Injections) describes physical tests to be performed for the purpose of enumerating subvisible particles within specific size ranges. Recently the FDA has published a Stimuli Article (reference USPC 30 (6) Pages 2272-2280) demonstrating that advances in apparatus and quality control merit ...

ByWIS Biomed


Continuous mixing systems for the production of pharmaceutical tablets and granulates

Continuous mixing systems for the production of pharmaceutical tablets and granulates

Own testing and model calculations demonstrate that their efficiency is determined not only by process parameters such as average residence time and metering constancy but also by the particle size distribution and the concentration range of the active substance. ...

ByGericke AG

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