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Pediatry Patient Articles & Analysis

19 articles found

Common Types of Excipients in Pharmaceutical Formulations

Common Types of Excipients in Pharmaceutical Formulations

In the pharmaceutical industry, excipients play a crucial role in the formulation of medicines. These inactive substances, which are combined with the active pharmaceutical ingredient (API), perform various functions that enhance the effectiveness, stability, and overall performance of drug products. Understanding the common types of excipients is essential for pharmaceutical scientists and ...

ByBOC Sciences


Hydrogen and Methane Breath Testing in Children: A Practical Guide

Hydrogen and Methane Breath Testing in Children: A Practical Guide

Hydrogen and methane breath testing (HMBT) is a non-invasive diagnostic tool frequently used to assess small intestinal bacterial overgrowth (SIBO) and carbohydrate malabsorption disorders such as lactose and fructose intolerance. Despite its widespread use in adults, its application in children is less standardised, and clinicians often face uncertainties about adapting adult protocols for the ...

ByBedfont Scientific Limited


Addressing Primary Care Challenges with the NObreath®

Addressing Primary Care Challenges with the NObreath®

FeNO Testing in Asthma Care Although airway eosinophilic inflammation is a key characteristic of asthma, there are few methods available to measure it. This inflammation can be assessed by measuring eosinophils and eosinophilic cationic protein (ECP) in sputum or by measuring ECP in blood samples1. However, these methods are considered time-consuming, expensive, and not readily available. For ...

ByBedfont Scientific Limited


Understanding the Different Levels of CPR Training

Understanding the Different Levels of CPR Training

CPR training is more than just a certification; it’s a crucial skill that can save lives in critical situations. In Kentucky, where industries range from manufacturing to healthcare, the demand for comprehensive CPR and first aid training is ever-present. The different levels of CPR training are designed to meet specific needs – from basic techniques for laypersons to advanced ...

ByRescue Solutions LLC


Application of Whole Plasmid Sequencing in Analyzing Drug Resistance Genes of Klebsiella pneumoniae

Application of Whole Plasmid Sequencing in Analyzing Drug Resistance Genes of Klebsiella pneumoniae

Klebsiella pneumoniae is a significant causative agent of hospital- and community-acquired infections, presenting with various clinical manifestations. Notably, the rapid spread of carbapenem-resistant K. pneumoniae (CRKP) has become a global threat, leading to high morbidity and mortality rates. In this context, researchers have employed high-throughput sequencing to investigate drug resistance ...

ByCD Genomics


Do you really have to sacrifice MRI image quality for speed?

Do you really have to sacrifice MRI image quality for speed?

To understand the significance of the SpinTech MRI STAGE software platform, it helps to begin by asking a question: Given that MRI is an incredibly powerful diagnostic tool for neurological diseases like Alzheimer’s, dementia, Parkinson’s and multiple sclerosis (MS), why have radiologists and neurologists had to choose between conducting faster MRI exams and obtaining higher-quality ...

BySpinTech, Inc.


No-touch Forehead Temperature Measurement in Two Clinical Settings

No-touch Forehead Temperature Measurement in Two Clinical Settings

Background. Healthcare personnel prefer devices that maximize efficiency while minimizing cross-contamination as well as cost. The Caregiver® (Thermomedics, Inc., Miami. FL), a new infrared non-contact forehead thermometer has been developed for clinical professional use. Our objective was to evaluate the clinical accuracy and repeatability of the Caregiver as compared to measurements ...

ByThermomedics, Inc.


FluGen Announces Completion of First Cohort in Age De-escalation Clinical Trial of M2SR Flu Vaccine Candidate in Pediatric Subjects Ages 6 Months to 17 Years

FluGen Announces Completion of First Cohort in Age De-escalation Clinical Trial of M2SR Flu Vaccine Candidate in Pediatric Subjects Ages 6 Months to 17 Years

MADISON, Wis., Sept. 7, 2022 /PRNewswire/ — FluGen, Inc., a clinical-stage vaccine company transforming vaccine efficacy in infectious respiratory diseases, today announced the completion of enrollment of the first cohort in an age de-escalation clinical trial of M2SR (M2 Deficient Single Replication) live virus vaccine, the company’s investigational supra-seasonal intranasal ...

ByFluGen, Inc.


How the Gut Adapts in Short Bowel Syndrome Patients

How the Gut Adapts in Short Bowel Syndrome Patients

Gut Adaptation; the body’s natural ability to “heal” itself. The human body is nothing short of miraculous. It can create life, perform incredible feats, and allow us to experience the world through a number of senses. But what happens when the body becomes damaged from illness or injury? Medical advancements have helped us come a long way in fighting disease, injury and ...

ByEclipse Regenesis


Accuracy of Pulse Oximeters Intended for Hypoxemic Pediatric Patients - Case study

Accuracy of Pulse Oximeters Intended for Hypoxemic Pediatric Patients - Case study

OBJECTIVES: Prior studies have shown inaccuracies in pulse oximetry readings at saturations less than 85%; however, no large studies have evaluated new sensors marketed for these low saturations. This study's purpose was to evaluate two sensors with claims of improved accuracy in children with saturations less than 85%. DESIGN: Prospective observational study. SETTING: Single institution; ...

ByMasimo Corp


LAG-3 antibody drug R&D boom   

LAG-3 antibody drug R&D boom  

On March 19, Bristol-Myers Squibb (BMS) announced that its dual immunotherapy combination Opdualag had received accelerated marketing approval from the FDA. Opdualag therapy is a fixed-dose combination of Relatlimab (anti-LAG3) and Nivolumab (anti-PD1) for the treatment of adult and pediatric patients 12 years of age and older with unresectable or metastatic melanoma, making LAG-3 the third ...

ByCreative Biolabs


Short Bowel or Short Fuse; Finding the patience to survive with a short gut

Short Bowel or Short Fuse; Finding the patience to survive with a short gut

A parents perspective If you have not had the chance to read A Parent’s Perspective: Our Son’s Short Bowel Syndrome Diagnosis, I encourage you to do so. While the goal is to give as much insight into Short Bowel Syndrome as possible, we want to steer clear of the boring clinical information online. From one Short Bowel Parent to another, trust me, you’ll have no better teacher ...

ByEclipse Regenesis


Techniques to Enhance Drug Solubility

Techniques to Enhance Drug Solubility

Solid preparations for oral administration for children have the advantages of convenient carrying and good stability, but for children, they are prone to dysphagia. The liquid dosage form for oral administration for children not only has benefits like large dispersion and fast absorption, but also can improve the bioavailability of some drugs, which has a greater development prospect and ...

ByCD Formulation


A Parent’s Perspective: Our Son’s Short Bowel Syndrome Diagnosis

A Parent’s Perspective: Our Son’s Short Bowel Syndrome Diagnosis

Chances are this is not the first blog you’re reading about Short Bowel Syndrome. And if you’re anything like myself or my wife, Google has been both your best friend and worst enemy lately. So I’m hoping that our story can help you navigate what can be a scary time, or at least let you know that you’re not alone. To be honest, we were stressed well before our ...

ByEclipse Regenesis


Cutaneous Patches to Monitor Myoelectric Activity of the Gastrointestinal Tract in Postoperative Pediatric Patients

Cutaneous Patches to Monitor Myoelectric Activity of the Gastrointestinal Tract in Postoperative Pediatric Patients

Abstract Purpose: Limited means exist to assess gastrointestinal activity in pediatric patients postoperatively. Recently, myoelectric gastrointestinal activity recorded by cutaneous patches has been shown in adult patients to be predictive of clinical return of gastrointestinal function postoperatively. The aim of this case series is to demonstrate the feasibility of this system in ...

ByG-Tech Medical


FDA clears first artificial iris by HumanOptics

FDA clears first artificial iris by HumanOptics

The first stand-alone prosthetic iris has received regulatory approval in the United States. CustomFlex Artificial Iris (HumanOptics) is a flexible silicone device indicated for adults and children with congenital aniridia or iris defects due to albinism, traumatic injury or surgical removal. “Today’s approval of the first artificial iris provides a novel method to treat iris ...

ByVEO Ophthalmics, LLC


Clinical validation of the Caregiver non-contact thermometer model PRO-TF300 in febrile and afebrile patients age 0 to < 18

Clinical validation of the Caregiver non-contact thermometer model PRO-TF300 in febrile and afebrile patients age 0 to < 18

Background: The CAREGIVER Thermometer Model PRO-TF300 (Thermomedics Inc., Delray Beach, FL) is a non-contact clinical professional thermometer used to read human body temperature in children and adults through the determination of infrared energy from the middle of the forehead. The purpose of this paper is to describe the methods and findings of the CAREGIVER’S validation for clinical use ...

ByThermomedics, Inc.


Many Faces of Sepsis (1): Cancer Therapy and Management Febrile Neutropenia - Case Study

Many Faces of Sepsis (1): Cancer Therapy and Management Febrile Neutropenia - Case Study

The purpose of this case study is to highlight ways in which medical algorithms can be integrated into the clinical decision making process. This case study is the first of a series focused on sepsis, a common but complex clinical problem. Use of algorithms can help healthcare providers diagnose sepsis early. Throughout our discussion, appropriate algorithms are suggested to help clinicians ...

ByThe Medical Algorithms Company Limited


High School Sports Concussions - Case Study

High School Sports Concussions - Case Study

High School Sports Concussions Lucy, a 15-year-old female is competing in a karate tournament a few hours from her home. She is a black belt and has been working very hard to place in the tournament. While in the semi-final match, she was caught with a round-house kick to her head. She was wearing headgear and she did not get knocked down. Following the match, which she lost, her parents and her ...

ByThe Medical Algorithms Company Limited

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