Physiological Response Articles & Analysis
18 articles found
The evaluation of cardiovascular toxicity is a significant challenge in drug development. Preclinical evaluation of cardiovascular safety involves a multifaceted approach, encompassing a plethora of in vitro and in vivo endpoints. These assessments continuously evolve, aiming to mitigate the incidence of cardiovascular toxicity that may emerge during clinical trials. To shed light on the ...
In certain circumstances, constitutive overexpression may lead to artifacts that could distort the intended physiological response. In such instances, IESCLs provide a regulated environment to monitor transient phenotypic responses. This ultimately allows for gene expressions to be modulated, granting precise insights into the subtleties of ...
Characteristics of Cytokines (1) Multipotency: Cytokines exhibit the ability to interact with different cell types, exerting their effects across a wide spectrum of cellular targets. (2) Overlap: There is often functional similarity or identity between two or more cytokines, leading to analogous biological effects. (3) Synergism: Certain cytokines are capable of enhancing the ...
In medicine, taking a holistic approach means treating the whole person - body, mind, spirit, and emotions - to achieve one’s optimal health and wellness. For example, if a patient comes in with a sharp, jabbing pain in his hand - a symptom of peripheral neuropathy - a holistic treatment plan may not only include pain relief medicine but also address underlying causes of pain. A holistic ...
With the current in vivo animal models, it is difficult to determine the mechanism of action of physiologic responses that translate to human medicine, as there are too many variables that can confound a researcher’s ability to draw definitive conclusions. Physiologic Relevance of Immortalized Cell Lines One alternative to in vivo animal ...
The Pearl River estuary, southern China, suffers from multiple sources of metal contamination as a result of the rapid industrial development in the region; but the biological impacts of contamination remain unknown. In the present study, a euryhaline oyster, Crassostrea hongkongensis, was collected from different sites of the Pearl River estuary; and various physiological (heart rate, ...
Changes in tissue transcriptomes and productivity of Arabidopsis thaliana were investigated during exposure of plants to two widely used engineered metal oxide nanoparticles, titanium dioxide (nano‐titanium) and cerium dioxide (nano‐cerium). Microarray analyses confirmed that exposure to either nanoparticle altered the transcriptomes of rosette leaves and roots, with comparatively larger ...
“What [Kriegel] is talking about is actually the next level where it isn’t necessarily purely pathogenic bacteria that trigger these responses,” said Silverman, who was not involved in the new study. ...
Autonomic system responses were measured with skin blood flow variations. Results from skin blood flow variations are presented and indicate a high correlation between the duration and amplitude of the response with the self-reported intensity and pleasantness of the stimulus. It also shows that physiological measurements enable the significant ...
Nickel can be gathered in agronomic soils by anthropogenic actions such as Ni-Cd batteries. In this study, the growth, physiological, photosynthetic and biochemical responses of Spinacia oleracea grown in Ni-spiked soil (0, 25, 50 and 100 mg Ni/Kg soil) at three levels of cotton-sticks-derived biochar “CSB” (0, 3 and 5 %) were evaluated. The results ...
A simulator study with 30 participants was conducted in which auditory icons were contrasted to abstract earcon sounds in more or less imminent collision scenarios and 3D sounds were tested against monophonic sounds in lane change scenarios. Self–report and physiological measures of emotional response as well as behavioural measures (e.g., brake ...
Knowledge of fruit physico–chemical properties and physiological responses is important for the design and development of appropriate postharvest handling and storage systems to reduce losses and maintain quality. ...
Nitrogen availability was equalized among treatments, and tall fescue physiological responses were measured under well-watered or moisture stress conditions. ...
This study was conducted to assess the usefulness of sewage sludge amendment (SSA) at 20 and 40% ratios for lady's finger (Abelmoschus esculentus L. var Varsha uphar) by evaluating the morphological, physiological, biochemical and yield responses. Lipid peroxidation, protein and antioxidant levels increased whereas photosynthetic rate, stomatal conductance and ...
Ice encasement and impermeable winter protective covers can induce anaerobic conditions on golf greens. We assessed plant survival and biochemical changes of annual bluegrass (Poa annua L.) and creeping bentgrass [Agrostis stoloniferous L. var. palustris (Huds.)] exposed to combinations of O2 and CO2 concentrations at low temperatures (1°C or –2°C). Results indicate that lack of O2 (anoxia) ...
Abstract Background: The objective of the study was to investigate the physiological responses of construction workers labouring in thermally stressful environments in the UAE using Thermal Work Limit (TWL) as a method of environmental risk assessment. ...
Sufferers are taught biofeedback strategies to regain some physiological management over their response to the situation. When these approaches fail, thought disruptive approaches such as eye movement desensitisation [9] are suggested. ...
Continuous ozone exposure at 0.3 ppm (v/v) (US-OSHA Threshold Limit Value for short term exposure) inhibited aerial mycelial growth and sporulation on ‘Elegant Lady’ peaches wound inoculated with Monilinia fructicola, Botrytis cinerea, Mucor piriformis, or Penicillium expansum and stored for 4 weeks at 5 °C and 90% relative humidity (RH). Aerial growth and sporulation, however, ...