Platelet Activation Articles & Analysis
5 articles found
Some studies have examined drug delivery systems using platelet endocytosis to absorb fluorescent beads and viral particles which get stored in platelet α-granules for subsequent release during platelet activation. ...
Ceramide and Cardiovascular Diseases Elevated ceramide concentrations can lead to apoptosis of vascular endothelial cells and regulate platelet activation and coagulation, leading to thrombosis. It also regulates angiotensin, which can lead to atherosclerosis and a number of cardiovascular diseases such as hypertension. ...
Abstract The goal of this study is to develop unique native endothelium mimicking nanomatrices and evaluate their effects on adhesion and spreading of human umbilical vein endothelial cells (HUVECs) and aortic smooth muscle cells (AoSMCs). These nanomatrices were developed by self-assembly of peptide amphiphiles (PAs) through a solvent evaporation technique. Three PAs, one containing the ...
Many of the heparin dependent antibodies, including those with the IgG isotype, are asymptomatic, and only a subgroup of antibodies is positive in platelet activation assays. What differentiates pathogenic from asymptomatic antibodies is not fully understood, with the exception that there is some relationship between antibody concentration and occurrence of HIT, ...
Lymphocyte membrane changes and increased lipid peroxidation were demonstrated due to free radical formation as well as elevated neutrophil peroxidase and catalase activities. In the reconstitution period, inhibition of the immune function was associated with lymphocyte subset changes such as decreased CD3+ and CD4+ cells counts and increased number of somatic mutations in ...