Preclinical Phase Articles & Analysis: Older
7 articles found
He has worked in the leading CROs in the industry and has assisted pharmaceutical companies with the drug development process with clinical trials, programs, and portfolio designs. His experience extends from preclinical, phases I through IV, biosimilar, and bioequivalent using fixed, adaptive designs, stand-alone, and master protocols in multiple therapeutic ...
ByStatsol
As summarized in the Table and illustrated in Figure 1, each of these mechanisms has a drug-based precedent and the devices are in various phases of clinical study. In general, in contrast to their drug-based precedents, which may have off-target and secondary mechanisms of action, these devices in principle more specifically target the pathophysiologically deranged mechanism of ...
So, I’ve spent the past year digging deep into drug databases and I’ve noticed there are three types of drug information: The chemical properties of a drug The effect a drug has on cell cultures and animals (preclinical research) The effect a drug has on humans (clinical research) Each type of information can be found on chemical, ...
The major preclinical phases of peptide drug discovery encompass initial target identification and validation, hit identification, high throughput screening, lead optimization, etc. ...
Everyone wants to be innovative, but rarely is innovation a lightning strike of genius – especially within the robotics industry. Instead, it is an intentional process and methodology. This process is refined and modified over time to enable an organization’s ability to think creatively and execute ...
Our focus on pain under this grant has led to the generation of preclinical datasets for both our Progenza™ and Sygenus platforms. ...
Other proteins with altered levels, such as Kunitz-type protease inhibitor 1 and beta-2-microglobulin, were not substrates in biochemical assays, suggesting an indirect affect of the MMPI, which might be important in drug development as biomarkers or, in preclinical phases, to predict systemic drug actions and adverse side effects. ...