Refine by
Rheumatoid Arthritis Articles & Analysis
36 articles found
l Cystic fibrosis (CF): Neutrophilic inflammation in the CF lung is exacerbated by high ELANE levels, promoting mucus hypersecretion, airway remodeling, and bacterial persistence. l Rheumatoid arthritis and vasculitis: ELANE damages endothelial barriers and exposes autoantigens, further fueling immune activation. ...
For example, in conditions like rheumatoid arthritis or lupus, researchers can pinpoint which autoantigens share similarities with microbial antigens. ...
Autoimmune Diseases: By analyzing cytokine imbalances, researchers can uncover mechanisms underlying diseases such as rheumatoid arthritis and lupus. Infectious Diseases: Cytokine panels provide insights into host-pathogen interactions and immune responses to infections. ...
By modulating inflammation, it could help restore balance in conditions like multiple sclerosis or rheumatoid arthritis. Uncovering the Secrets of TNC Protein Despite its importance, much about TNC protein remains a mystery. ...
They can usually be used to treat rheumatoid arthritis. These drugs are used to treat rheumatoid arthritis. ...
Another VHH domain binds to human serum albumin (HSA), and the drug is indicated for rheumatoid arthritis (RA). Ozoralizumab was developed by Ablynx, and Taisho obtained the development authorization from Japan. ...
Abstract Background: Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by chronic inflammation of synovial joints. ...
Consequently, CAR-T cell therapy targeting CD19 has gained widespread use as a treatment for CD19-positive CLL, showing promising therapeutic outcomes. 3) Autoimmune Diseases: Autoimmune diseases stem from the immune system's attack on its own healthy tissues and organs. Conditions like rheumatoid arthritis and systemic lupus erythematosus involve abnormal ...
Hip replacement surgery has been a life-changing procedure for individuals grappling with debilitating hip conditions like osteoarthritis, rheumatoid arthritis, or hip fractures. Over the years, continuous strides in medical technology have ushered in substantial enhancements in hip prostheses, offering patients the prospect of regaining mobility, alleviating ...
Its distinctive fruit, covered with a tough shell and burrs, has been used for centuries in traditional medicine for headaches, nasal congestion, skin pigmentation disorders, tuberculosis-related diseases and rheumatoid arthritis. In recent years, scientists have explored its potential use in treating rheumatoid arthritis and ...
Granulocyte colony-stimulating factor (G-CSF) enhances granulocyte function, while IL-7 heightens macrophage cytotoxic activity and induces monocyte cytokine secretion. Cytokine Involvement in Rheumatoid Arthritis (RA) RA, an immune-related polyarticular inflammatory disorder, involves a spectrum of cytokines, including IL-1B, IL-6, IL-12, IL-15, and ...
Clinical Applications of MMP-3 MMP-3 and Rheumatoid Arthritis (RA) Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease characterized by synovial cell proliferation and infiltration of lymphocytes, leading to destruction of joint cartilage and bone erosion. ...
Autoimmune disease target - IL-17 Family IL-17 plays an important role in promoting autoimmune diseases such as psoriasis, psoriatic arthritis, and ankylosing spondylitis (AS). Currently, five large-molecule biopharmaceuticals targeting IL-17/IL-17R are available worldwide, including four IL-17 monoclonal antibodies and one IL-17RA monoclonal antibody, namely ...
In addition to being a target for skin inflammatory diseases, IL-36 can also be an effective drug target for inflammatory bowel disease (IBD), rheumatoid arthritis, and other inflammatory diseases. Related Recombinant Proteins Offered by Beta LifeScience IL-1 SuperFamily Human IL-1 alpha/IL -1F1 Biotinvlated Human IL-1 alpha/IL-1F1(C-Avi) Mouse IL-1 alpha/IL ...
These diseases include: Asthma Psoriasis Lupus Rheumatoid arthritis Multiple sclerosis ...
It’s reported that persistent activation of NF-κB can lead to chronic inflammation, such as rheumatoid arthritis, Parkinson's disease, and inflammatory bowel disease. ...
Variants in HLA genes are now thought to increase susceptibility to a variety of immune-mediated diseases, such as rheumatoid arthritis and diabetes mellitus type 1. Rapid advances in sequencing technology have changed the way of querying the role of HLAs in clinical and basic studies. ...
The complement system is involved in the progression of many diseases, and complement activation is associated with several common autoimmune diseases, such as systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA), ophthalmic diseases such as uveitis and glaucoma, renal diseases including C3 glomerulopathy, atypical hemolytic uremic syndrome and IgA ...
Oncology and autoimmune diseases (rheumatoid arthritis, multiple sclerosis) are currently among the clinical pipeline indications for LAG-3 which acts as an immunomodulator in a variety of tumors, including leukemia, non-small cell lung cancer, colon cancer, pancreatic cancer, and head and neck cell cancer. ...
Additionally, the robotic pill is designed to deliver large molecule drugs, making it especially useful for therapies such as basal insulin, human growth hormones, rheumatoid arthritis medications, Humira and other biosimilars. One of the biggest announcements in the Q4/2021 year-end report was that last month, Rani came out with a next-gen version: the ...