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Sample Processing Articles & Analysis
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However, definitive diagnosis relies on biopsy, which can be performed through fine needle aspiration, core needle biopsy, or excisional biopsy. Once a sample is obtained, FFPE processing preserves cellular integrity, allowing for detailed histopathological examination. ...
Antibody drugs have shown remarkable therapeutic effects in the treatment of various diseases, such as cancer, autoimmune diseases, inflammatory diseases, immune regulation, and ophthalmic diseases.In the production process of antibody drugs, the culture medium plays a very important role. ...
This may involve adding extra amino acids, sugars, or other growth factors to enhance yield.Monitoring By-Products and ImpuritiesHarmful by-products or impurities may be produced during the culture process, and these can be monitored through the analysis of the culture medium and cell culture fluid. ...
The measurement of collagen can help researchers and physicians understand the pathological process of related diseases (such as osteoporosis, arthritis, skin aging etc.), and also aid in drug development and other biomedical research.The measurement of collagen can usually be carried out through several different methods:Mass Spectrometry1. ...
Oxidative phosphorylation is the process by which mitochondria produce ATP (adenosine triphosphate) in the cellular respiration chain. ...
The study of gene TR changes in different samples is important for understanding the molecular mechanism of ncRNAs. ...
These glycan structures have a significant impact on the immunogenicity and stability of the vaccine. During the production process, the content and type of monosaccharides may be affected by many factors, such as the type of host cell, culture conditions, protein folding, and glycan assembly, etc. ...
However, in the research and production process of peptide drugs, precise analysis must be performed to determine their purity, structure, charge, and other characteristics to ensure their efficacy and safety. ...
Next-Generation Transcriptome Sequencing The key differences between Nanopore full-length transcriptome sequencing and next-generation transcriptome sequencing platforms are primarily related to their sequencing technology, read length, sample processing, and data output. Nanopore Sequencing: Enhancing Transcript Expression Quantification Nanopore full-length ...
The cryogenic process is a method of freezing and storing samples that involves cooling the temperature of biological materials to stop normal cellular processes and prevent sample degradation for long-term storage. The cryogenic process and cryo storage are ideal solutions for the storage of biological ...
Since the 19th century, the practice of tissue processing has remained largely unchanged, resulting in solidified, paraffin-embedded tissue blocks for sectioning. As staining procedures have advanced and immunohistochemistry is becoming more widely used, high-quality tissue sections are paramount for accurate interpretation of disease ...
The Holiday season often brings mixed feelings for many. While it can be a time of relaxation with friends and family for some, for others, preparing for this time means ensuring business continuity despite a typical slow down. This can be a source of undue stress if it is not suitably planned for. ...
The reader analyzes a patient’s sample by performing a displacement assay based on evanescent wave technology, an established biochemical process that is proven and fast (see sidebar, “Bio-optical processing”). ...
Automation now eases manual processes in so many aspects of society, from smart home switches to manufacturing lines. It’s also helping those working in molecular biology, biotech and pharmaceuticals to find new efficiencies and cost savings. So why consider an upgrade from manual pipetting in your lab? ...
Sphingolipids play important roles in various life processes, including tumor evolution, the development of multi-drug resistance in tumor cells, vascular endothelial cell signaling, atherosclerosis formation, regulating the development and lifespan of organisms, as well as viral and bacterial infections. ...
While ultra-low temperature preservation is highly effective for a wide range of sample types, the process can have an unintended impact if not executed properly. ...
I work primarily to help customers gain maximum benefit from the use of the PierianDx Clinical Genomics Workspace platform, whether it be demonstrating different aspects of the platform or troubleshooting minor issues. My work ranges from processing sample files, preparing example clinical reports, explaining features, listening to customers and prospective ...
As the world opens up over the coming months and years, there will be countless plane journeys to see loved ones, meet new family members and travel for work and leisure. Many of these travellers will first need to provide evidence of a negative PCR test to show they pose a minimal COVID-19 transmission risk. Time is proving of the essence for testing. With reports of multi-hour queues at ...
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Mic qpcr cycler and Myra liquid handler have been put through their paces in COVID-19-testing field trials in regional Western Australia and found to be noticeably robust, rapidly deployable and flexible. These results have been outlined in a recent paper, Development, deployment and in-field demonstration of mobile corona virus SARS-CoV-2 Nucleic acid amplification test, published by Paton, ...