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Subcutaneous Injection Articles & Analysis

15 articles found

Pharmacokinetic Characteristics of Monoclonal Antibody Drugs

Pharmacokinetic Characteristics of Monoclonal Antibody Drugs

Therefore, most mAb drugs are administered by intravenous injection, and a small part is administered by subcutaneous or intramuscular injection. ...

ByCreative Proteomics


A Difficult Needle to Thread

A Difficult Needle to Thread

For me, being a trans man means having to take a weekly dosage of testosterone, administered by myself, intramuscularly into my thigh. Intramuscular injections are a little different than what you might be thinking of when I say ...

ByPortal Instruments, Inc.


What Is Collagen?

What Is Collagen?

There are also many different ways to supplement collagen on the market, such as eating collagen-containing foods, direct subcutaneous injection, and oral small-molecule collagen peptides. Consuming collagen supplements, because a large part of it will be filtered out by the human digestive system, the amount that can really reach the skin and play a role is very ...

ByCreative Enzymes


Proximal Femur Responses to Sequential Therapy With Abaloparatide Followed by Alendronate in Postmenopausal Women With Osteoporosis by 3D Modeling of Hip Dual-Energy X-Ray Absorptiometry (DXA)

Proximal Femur Responses to Sequential Therapy With Abaloparatide Followed by Alendronate in Postmenopausal Women With Osteoporosis by 3D Modeling of Hip Dual-Energy X-Ray Absorptiometry (DXA)

Correlation analyses were also performed to investigate the extent to which BMD gains with ALN during ACTIVExtend relate to levels of bone turnover markers at the time of therapeutic transition to alendronate from ABL or PBO treatment. 2 Patients and Methods 2.1 ACTIVE trial ACTIVE was a phase 3, double-blind, placebo-controlled trial.(2) A total of 2463 postmenopausal women aged 49 to ...

By3D-Shaper Medical SL


Rani developing technology for oral delivery of injectable biologics

Rani developing technology for oral delivery of injectable biologics

“We have taken a different approach, using technology with the RaniPill, instead of chemistry and we are getting bioavailability and absorption rates that rival subcutaneous injection of biologics,” he adds. Mr. Imran, a former venture capitalist and former VP of corporate strategy for Rani, says patients prefer pills over ...

ByRani Therapeutics


Raising Awareness on the Challenges of Injections: `My First Injection`

Raising Awareness on the Challenges of Injections: `My First Injection`

Portal Instruments: That’s scary for your first time injecting! Can you walk me through the injection day? Jody: This past Saturday was the first time that I had to inject. ...

ByPortal Instruments, Inc.


Drug Delivery: What do Patients and Providers Want?

Drug Delivery: What do Patients and Providers Want?

However, given the amount of time required per IV placement and the IV placement failure rate, it is not surprising that patients prefer subcutaneous (SC) delivery over IV infusion.4 The Step Forward With SC Administration SC administration enables more flexible delivery options for both the patient and the provider. ...

ByEnable Injections


Needles and Pills: Rani Therapeutics Is Making Encapsulated Oral Biologics

Needles and Pills: Rani Therapeutics Is Making Encapsulated Oral Biologics

Their novel, patented platform technology replaces subcutaneous or IV injection of biologics with oral dosing. The RaniPill capsule is an orally ingestible vehicle, approximately the size of a standard fish oil or calcium pill, which is designed to automatically administer a precise therapeutic dose of medication upon deployment in the small intestine . . ...

ByRani Therapeutics


Rani Therapeutics offers breakthrough capsule for patients with chronic conditions

Rani Therapeutics offers breakthrough capsule for patients with chronic conditions

Rani Therapeutics offers a breakthrough capsule, the RaniPill which could change the way patients with chronic conditions take medication by eliminating the need for painful injections. Rani Therapeutics is a clinical-stage biotherapeutics company offering an alternative to painful injections for patients with chronic conditions such as neuroendocrine ...

ByRani Therapeutics


Rani Therapeutics Debuts on the Nasdaq: What uou should know About the Biopharma

Rani Therapeutics Debuts on the Nasdaq: What uou should know About the Biopharma

Rani, A Platform Technology Company: Rani's proprietary platform technology, the RaniPill capsule, intends to replace subcutaneous or intravenous injections of biologics with oral dosing. RaniPill helps convert injectable biologic drugs such as TNF-alpha inhibitors, interleukin antibodies and basal insulin, among others, into pills. "Our ...

ByRani Therapeutics


Rani Therapeutics prices $73M IPO for robotic drug-delivery pill tech

Rani Therapeutics prices $73M IPO for robotic drug-delivery pill tech

“That’s in line with subcutaneous injections, which ranged between 40% and 80%,” said Talat Imran, the company’s CEO. ...

ByRani Therapeutics


Treos Bio Announces the Publication of Preclinical Data in Frontiers in Genetics Showing its COVID-19 Peptide Vaccine Mimics the Diversity of T Cell Immunity Produced by Natural SARS-CoV-2 Infection

Treos Bio Announces the Publication of Preclinical Data in Frontiers in Genetics Showing its COVID-19 Peptide Vaccine Mimics the Diversity of T Cell Immunity Produced by Natural SARS-CoV-2 Infection

” Article highlights include: For the first time, individuals’ complete HLA-genotype and ethnicity were considered for the selection of shared SARS-CoV-2-specific epitopes PolyPEPI-SCoV-2 vaccination will likely elicit multi-antigenic T cell responses in 98% of individuals, independent of ethnicity (unlike the commonly used epitope selection approach based only on frequent HLA ...

ByTreos Bio Limited


Abstract 9761: Novel Modulators of Low Density Lipoprotein Receptor Metabolism

Abstract 9761: Novel Modulators of Low Density Lipoprotein Receptor Metabolism

Furthermore, in a two week animal study, subcutaneous injection of 4 mg/kg of one of these compounds resulted in a 32% reduction of the total cholesterol level in mice fed a high fat/high cholesterol diet as compared to 27% cholesterol reduction obtained with 40 mg/kg Atorvastatin. ...

ByShifa Biomedical Corporation


Abstract 15053: New Insights into the Development of the Protease Proprotein Convertase Subtilisin-Like Kexin Type 9 Antagonists

Abstract 15053: New Insights into the Development of the Protease Proprotein Convertase Subtilisin-Like Kexin Type 9 Antagonists

Several pharmaceutical companies have developed injectable mAb PCSK9 antagonists. Instead, we have been developing small molecule, orally bioavailable PCSK9 antagonists. ...

ByShifa Biomedical Corporation


In vitro and in vivo evaluation of an injectable premixed calcium phosphate cement; cell viability and immunological response from rat

In vitro and in vivo evaluation of an injectable premixed calcium phosphate cement; cell viability and immunological response from rat

By using premixed calcium phosphate cement (CPC) the handling properties of the cement are drastically improved, which is a challenge for traditional injectable CPC. In this article, a premixed acidic CPC has been compared to a conventional water mixed brushite cement to evaluate whether the premixed concept affects the biological response. ...

ByInderscience Publishers

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