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Tissue Remodeling Articles & Analysis

13 articles found

A Silent Architect of Post-Surgical Healing: The Extracellular Matrix

A Silent Architect of Post-Surgical Healing: The Extracellular Matrix

In surgical tissue recovery, focus is on controlling infection, managing inflammation, and ensuring wound closure. Beneath the surface—anatomically and biologically— the extracellular matrix (ECM) is undergoing remodeling ensure long-term tissue integrity. The ECM is a dynamic, biologically active network that orchestrates the entire ...

BySanara MedTech Inc.


ELANE Protein: A Dual-Edged Regulator of Inflammation, Immunity, and Tissue Remodeling

ELANE Protein: A Dual-Edged Regulator of Inflammation, Immunity, and Tissue Remodeling

It plays a pivotal role in the host defense system by degrading bacterial proteins, remodeling extracellular matrices, and shaping inflammatory responses. However, the same proteolytic activity that protects against pathogens can, when unregulated, contribute to tissue injury, autoimmune inflammation, and chronic disease progression. ...

ByCreative BioMart


The Vital and Complex Role of Elastase

The Vital and Complex Role of Elastase

By degrading harmful entities, elastase helps in modulating immune responses and tissue repair. Elastase and Tissue Remodeling Elastase's ability to degrade elastin makes it significant in tissue remodeling and repair. ...

ByCreative Enzymes


TNC Protein: The Hidden Hero of Cellular Communication

TNC Protein: The Hidden Hero of Cellular Communication

While it was first discovered in gliomas (a type of brain tumor), TNC protein is present in a variety of tissues, especially during embryonic development and tissue remodeling after injury. ...

ByCreative BioMart


Matrix Metalloproteinases (MMPs) - Structure, Sources and Functions

Matrix Metalloproteinases (MMPs) - Structure, Sources and Functions

They are present in most connective tissues. MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-12, MMP-13, and MT1-MMP and MT3-MMP are expressed in various vascular tissues and cells. ...

ByCreative Proteomics


Cytokines: The Master Regulators of Immunity and Inflammation

Cytokines: The Master Regulators of Immunity and Inflammation

Serving as intermediaries, they synchronize various cell functions to elicit the body's defense mechanisms against infections, tissue restoration, and wound healing. Types of Cytokines Cytokines are classified into various families based on their structural similarities and biological functions. ...

ByCreative BioMart


What is Nano Dressing?

What is Nano Dressing?

Features of Nano Dressings Dressing is a kind of medical material that can replace damaged skin or tissue, and can promote wound healing and tissue repair, such as gauze, bandage, sponge. ...

ByCD Bioparticles


Introduction to Lipogenesis, Lipid Anabolism and Catabolism

Introduction to Lipogenesis, Lipid Anabolism and Catabolism

Obesity is caused by excessive expansion of white adipose tissue. When nutrient intake is excessive, adipose tissue expands through either adipocyte hypertrophy or hyperplasia. Among them, adipocyte hyperplasia can effectively avoid pathological adipose tissue remodeling, thus maintaining the normal metabolic function of adipose ...

ByCreative Proteomics


Discovery of Bispecific Antibodies and Immune Checkpoint Inhibitors That Kill Glioblastoma Cells and Melanoma Cells, and Block the Metastasis of Malignant Melanoma Cells to the Lung by Over 90%

Discovery of Bispecific Antibodies and Immune Checkpoint Inhibitors That Kill Glioblastoma Cells and Melanoma Cells, and Block the Metastasis of Malignant Melanoma Cells to the Lung by Over 90%

Chitinase 3-like-1 (CHI3L1) is a member of the 18 glycosyl hydrolase gene family that is readily detected in the circulation of normal individuals and expressed at exaggerated levels in the circulation of individuals with diseases characterized by inflammation, tissue remodeling and or cancers. Discoveries Recent studies from our laboratory have demonstrated ...

ByOcean Biomedical


Silk Fibroin Enhances Tendon Repair and Tissue Regeneration

Silk Fibroin Enhances Tendon Repair and Tissue Regeneration

“At the same time, gelatin-based polymers have advantages in cell attachment and tissue remodeling, but insufficient mechanical strength in regenerating hard tissues such as tendons. ...

ByMatexcel


Prolotherapy and the Use of Sugars in Orthopedics

Prolotherapy and the Use of Sugars in Orthopedics

Prolotherapy has been a part of modern orthopedic practices since the 1940s. It is growing in popularity not just in the U.S., but globally as well. Also known as “regenerative injection therapy” (RIT), prolotherapy is a procedure used to treat musculoskeletal conditions including tendinopathies, osteoarthritis, and chronic pain of the cervical spine, lumbar spine, and pelvis (Sit et ...

ByMolecular Matrix, Inc.


New Cell Contenders in the CAR Field (Part 2)

New Cell Contenders in the CAR Field (Part 2)

Scientists typically characterize macrophages based on various surface markers and secreted factors that are closely associated with inflammation pathogen defense, and tumor defense (M1), anti-inflammation and wound healing (M2a), Immunoregulation (M2b), Immunosuppression and tissue remodeling (M2c), and angiogenesis and tumor promotion (M2d) [1]. ...

ByIndee Labs


	 Utilization of a 3D bioprinted liver tissue model to evaluate the antifibrotic effects of an ALK5 inhibitor in a TGFß-induced model of hepatic fibrosis

Utilization of a 3D bioprinted liver tissue model to evaluate the antifibrotic effects of an ALK5 inhibitor in a TGFß-induced model of hepatic fibrosis

Publication Summary: Compound induced chronic liver injury can lead to initiation of profibrotic processes resulting in sustained production of growth factors and profibrotic cytokines where inflammation, tissue remodeling and repair pathways are activated simultaneously to counteract the injury. ...

ByOrganovo Holdings Inc.

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