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Tumor Necrosis Factor Alpha Articles & Analysis: Older

12 articles found

Differentiation and Functions of Th17/Treg Cytokines

Differentiation and Functions of Th17/Treg Cytokines

Th precursor cells are regulated by different cytokines and transcription factors and can differentiate into CD4+ T cell subsets such as Th1, Th2, Th17 and Treg cells. ...

ByCreative Proteomics


Unraveling the Mysteries of TREM1 Protein: A Key Player in Inflammation and Disease

Unraveling the Mysteries of TREM1 Protein: A Key Player in Inflammation and Disease

Upon activation, it potentiates the production of pro-inflammatory cytokines, such as tumor necrosis factor-alpha (TNF-α), interleukin-1 beta (IL-1β), and interleukin-6 (IL-6), thereby exacerbating the inflammatory cascade. ...

ByCreative BioMart


Influenza A virus replication has a stronger dependency on Raf/MEK/ERK signaling pathway activity than SARS-CoV-2

Influenza A virus replication has a stronger dependency on Raf/MEK/ERK signaling pathway activity than SARS-CoV-2

Then, cells were stimulated by the addition of tumor necrosis factor alpha (TNF-α) (Sigma-Aldrich, St. Louis, Missouri, USA) for 30 min at 37°C, 5% CO2, followed by treatment with different zapnometinib concentrations and a DMSO (solvent) control for 1 h. ...

ByAtriva Therapeutics GmbH


Autoimmune Diseases Targets

Autoimmune Diseases Targets

TSLP and TH2 In allergic inflammation, TSLP can strongly activate DCs (dendritic cells), which subsequently drive the development of naive TH cells into "inflammatory" effector TH2 cells that express classical TH2 cytokines, pro-inflammatory tumor necrosis factor-alpha (TNF-α), and anti-inflammatory IL-10. ...

ByBeta Lifescience


Inflammatory Cytokines Profile

Inflammatory Cytokines Profile

Tumor necrosis factor-α (TNF-α) Depending on the cell source and molecular structure, it can be divided into alpha and beta types. ...

ByCreative Proteomics


A Novel, High-Throughput Platform to Characterize Novel IBD Therapeutics

A Novel, High-Throughput Platform to Characterize Novel IBD Therapeutics

Tumor Necrosis Factor Alpha (TNF-a) is a potent cytokine that is over-expressed by cells during chronic intestinal inflammation. ...

ByAltis Biosystems


Roseburia spp. Abundance Associates with Alcohol Consumption in Humans and Its Administration Ameliorates Alcoholic Fatty Liver in Mice

Roseburia spp. Abundance Associates with Alcohol Consumption in Humans and Its Administration Ameliorates Alcoholic Fatty Liver in Mice

The incidence rates of ALDs are strongly affected by several risk factors such as the quantity and pattern of alcohol consumption, gender, ethnicity, diet, and host genetic factors (O'Shea et al., 2010, Stickel and Hampe, 2012). ...

ByKoBioLabs


The putative α-1,2-mannosyltransferase AfMnt1 of the opportunistic fungal pathogen aspergillus fumigatus is required for cell wall stability and full virulence

The putative α-1,2-mannosyltransferase AfMnt1 of the opportunistic fungal pathogen aspergillus fumigatus is required for cell wall stability and full virulence

In this study, we investigated the putative {alpha}-1,2-mannosyltransferase AfMnt1 of the human pathogenic mold Aspergillus fumigatus. ...

ByAmerican Society for Microbiology (ASM)


Suppressive effect on activation of macrophages by lactobacillus casei strain shirota genes determining the synthesis of cell wall-associated polysaccharides

Suppressive effect on activation of macrophages by lactobacillus casei strain shirota genes determining the synthesis of cell wall-associated polysaccharides

By adding heat-killed mutant cells to mouse macrophage cell lines or to mouse spleen cells, the production of tumor necrosis factor alpha, interleukin-12 (IL-12), IL-10, and IL-6 was more stimulated than by wild-type cells. ...

ByAmerican Society for Microbiology (ASM)


Biological responses in low-dose range

Biological responses in low-dose range

Out of the wealth of biological responses a few have been selected for discussion, namely, those which point to sensitive cellular reactions with possible consequences, or, those which might be promising in occupational medicine as indicators of a possible burden to persons, radiological or nuclear workers, and which might be used in the future as a routine laboratory technique in assessment of ...

ByInderscience Publishers


RelB Modulation of Ikappa Balpha Stability as a Mechanism of Transcription Suppression of Interleukin-1alpha (IL-1alpha ), IL-1beta , and Tumor Necrosis Factor Alpha in Fibroblasts

RelB Modulation of Ikappa Balpha Stability as a Mechanism of Transcription Suppression of Interleukin-1alpha (IL-1alpha ), IL-1beta , and Tumor Necrosis Factor Alpha in Fibroblasts

Members of the NF-B/RelB family of transcription factors play important roles in the regulation of inflammatory and immune responses. ...

ByAmerican Society for Microbiology (ASM)


Relb modulation of ib stability as a mechanism of transcription suppression of interleukin-1 (il-1), il-1, and tumor necrosis factor alpha in fibroblasts

Relb modulation of ib stability as a mechanism of transcription suppression of interleukin-1 (il-1), il-1, and tumor necrosis factor alpha in fibroblasts

Members of the NF-B/RelB family of transcription factors play important roles in the regulation of inflammatory and immune responses. ...

ByAmerican Society for Microbiology (ASM)

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