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Vaccine Candidate Articles & Analysis

22 articles found

Tissue Cross-Reactivity Studies: An Overview

Tissue Cross-Reactivity Studies: An Overview

It allows for the identification of suitable donors and improved matching processes, thereby enhancing graft survival rates. Implications for Vaccine Development In vaccine development, concerns about cross-reactivity can influence the safety and effectiveness of the vaccine. Researchers aim to create vaccines that elicit strong ...

ByCreative Bioarray


Research Progress on Aluminum Adjuvants and Their Mechanisms of Action

Research Progress on Aluminum Adjuvants and Their Mechanisms of Action

However, despite the fact that aluminum adjuvants in vaccines have been used in enhancing vaccine immune responses for nearly decades, the molecular mechanisms of aluminum adjuvants are still not fully understood. ...

ByBOC Sciences


Research And Development of Infectious Disease Vaccines

Research And Development of Infectious Disease Vaccines

As of January 1, 2023, global vaccine development includes a total of 966 vaccine candidates, of which 23% (220) are traditional inactivated or attenuated vaccines. ...

ByBiopharma PEG Scientific Inc


Ending tuberculosis by 2030: Are we close?

Ending tuberculosis by 2030: Are we close?

Interestingly, an investigational tuberculosis vaccine candidate was found to be significantly effective against the disease in the trial phase conducted in Kenya and Zambia, making it a potential vaccine in the future. ...

ByB Medical Systems


Vaccine Projects

Vaccine Projects

Abera’s vaccine delivery platform works as a plug-and-play system where known or novel antigens can be engineered onto our delivery platform to create effective, multivalent vaccines that are cost-effective and fast to produce. We actively work together with academia and industry to enable the use of our vaccine delivery platform in design ...

ByAbera Bioscience AB


FluGen Announces Completion of First Cohort in Age De-escalation Clinical Trial of M2SR Flu Vaccine Candidate in Pediatric Subjects Ages 6 Months to 17 Years

FluGen Announces Completion of First Cohort in Age De-escalation Clinical Trial of M2SR Flu Vaccine Candidate in Pediatric Subjects Ages 6 Months to 17 Years

“The M2SR vaccine candidate has already shown a robust safety profile in adults, and we look forward to advancing scientific understanding of the potential benefits of M2SR in ...

ByFluGen, Inc.


Rational Vaccines Announces a Clinical Trial to Determine Baseline Characteristics of Patients Diagnosed With Recurrent Symptomatic Herpes Simplex Type 2 (HSV-2) Virus

Rational Vaccines Announces a Clinical Trial to Determine Baseline Characteristics of Patients Diagnosed With Recurrent Symptomatic Herpes Simplex Type 2 (HSV-2) Virus

Results will inform protocol design of Phase 1/2 clinical trial of Company's lead HSV-2 therapeutic vaccine candidate WOBURN, Mass. and OXFORD, England, Aug. 15, 2022 /PRNewswire/ -- Rational Vaccines, a company focused on revolutionizing the treatment and prevention of herpes to eradicate the disease, today announced the launch of a clinical ...

ByRational Vaccines, Inc.


Rational`s Experimental Herpes Vaccine Shows Preclinical Promise

Rational`s Experimental Herpes Vaccine Shows Preclinical Promise

Rational Vaccines' experimental vaccine candidate for herpes simplex virus type 2 (HSV-2), the primary cause of genital herpes, is showing promise in preclinical studies. Massachusetts-based Rational Vaccines said findings from a pilot study funded by the National Institutes of Health showed that RVX201, its lead ...

ByRational Vaccines, Inc.


RVx201 Herpes Vaccine

RVx201 Herpes Vaccine

NLS) have provided the following observations: Mice vaccinated with HSV-2 0?NLS showed an improved antibody response compared to vaccination with a subunit vaccine candidate, Mice immunized with HSV-2 ...

ByRational Vaccines, Inc.


Nipah virus glycoprotein structure suggests therapeutic strategies

Nipah virus glycoprotein structure suggests therapeutic strategies

People infected with either of these diseases have a 50% to 100% chance of dying. There is already a vaccine approved for use on horses and a modified vaccine has entered human clinical trials. ...

ByCreative Biostructure


A Brown pathology professor may have developed a revolutionary new approach to battling one of the world’s deadliest diseases

A Brown pathology professor may have developed a revolutionary new approach to battling one of the world’s deadliest diseases

After being exposed to malaria, control monkeys that had not been vaccinated developed parasite levels three and a half times that of the vaccinated monkeys. ...

ByOcean Biomedical


FluGen Announces Publication of Positive Results from Phase 2 Human Challenge Study of Its M2SR Vaccine Candidate Against Highly Drifted Strain of H3N2 Influenza Virus

FluGen Announces Publication of Positive Results from Phase 2 Human Challenge Study of Its M2SR Vaccine Candidate Against Highly Drifted Strain of H3N2 Influenza Virus

“Current vaccines are strain-specific and in recent years they have had low efficacy against H3N2 influenza, especially when the vaccine is mismatched to circulating virus,” said Dr. ...

ByFluGen, Inc.


Treos Bio Announces the Publication of Preclinical Data in Frontiers in Genetics Showing its COVID-19 Peptide Vaccine Mimics the Diversity of T Cell Immunity Produced by Natural SARS-CoV-2 Infection

Treos Bio Announces the Publication of Preclinical Data in Frontiers in Genetics Showing its COVID-19 Peptide Vaccine Mimics the Diversity of T Cell Immunity Produced by Natural SARS-CoV-2 Infection

LONDON, June 28, 2021 (GLOBE NEWSWIRE) – Treos Bio Limited (“Treos”), a clinical stage biotechnology company using data science and proprietary biomarkers to develop precision off-the-shelf and personalized peptide cancer immunotherapies, today announced the publication of a peer-reviewed article titled “A Peptide Vaccine Candidate ...

ByTreos Bio Limited


FluGen Awarded US Department of Defense Funding to Conduct Clinical Study Evaluating Investigational M2SR Flu Vaccine and Current Standard-of-Care High Dose Vaccine

FluGen Awarded US Department of Defense Funding to Conduct Clinical Study Evaluating Investigational M2SR Flu Vaccine and Current Standard-of-Care High Dose Vaccine

This study will evaluate a monovalent H3N2 flu vaccine candidate, as compared to a licensed quadrivalent vaccine that is considered the current standard of care for adults aged 65 and above. ...

ByFluGen, Inc.


Micron developing microneedle technology for self-administration of vaccines and therapeutics

Micron developing microneedle technology for self-administration of vaccines and therapeutics

The study demonstrated that, following a vaccination using Micron’s technology, the immune response was as strong, or stronger, than vaccination by intramuscular injection. In addition, while the safety profile for Micron’s technology and intramuscular vaccination were similar, a survey showed a strong preference for Micron’s ...

ByMicron Biomedical, Inc.


The race to a vaccine - unintended consequences?

The race to a vaccine - unintended consequences?

A gold rush is on to find a vaccine for COVID-19. According to the World Health Association (WHO) in early May, there are more than 100 projects around the world centered on the development of a vaccine for the coronavirus. Eight candidate vaccines are already being tested in people in clinical trials. Once an effective ...

ByVistex Inc


UW–Madison, FluGen, Bharat Biotech to develop CoroFlu, a coronavirus vaccine

UW–Madison, FluGen, Bharat Biotech to develop CoroFlu, a coronavirus vaccine

UW–Madison, FluGen, Bharat Biotech to develop CoroFlu, a coronavirus vaccineTweet this CoroFlu will build on the backbone of FluGen’s flu vaccine candidate known as M2SR. Based on an invention by UW­Madison virologists and FluGen co-founders Yoshihiro Kawaoka and Gabriele Neumann, M2SR is a self-limiting version of the influenza virus that ...

ByFluGen, Inc.


Industry innovations for an equitable global distribution of COVID-19 vaccine

Industry innovations for an equitable global distribution of COVID-19 vaccine

With researchers ramping up efforts to develop a COVID-19 vaccine, progress has been achieved at unprecedented speed. In just two months, the first vaccine candidate entered clinical trials. ...

ByB Medical Systems


MSD Wellcome Trust Hilleman Laboratories, India - Case Study

MSD Wellcome Trust Hilleman Laboratories, India - Case Study

“With the spray drying technology, we have been able to achieve positive outcomes on our flagship vaccine candidate and are planning to extend the technology to other antigens and biopharmaceuticals as ...

ByBUCHI


Vaccine-induced antibodies target sequestered viral antigens to prevent ocular HSV-1 pathogenesis, preserve vision, and preempt productive neuronal infection

Vaccine-induced antibodies target sequestered viral antigens to prevent ocular HSV-1 pathogenesis, preserve vision, and preempt productive neuronal infection

Here, we tested a prophylactic live-attenuated vaccine against herpes simplex virus type 1 (HSV-1), a widespread human pathogen that can cause corneal blindness. ...

ByRational Vaccines, Inc.

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