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Vaccine Strain Articles & Analysis

7 articles found

A Milestone in Global Health: A New Polio Vaccine Approved for Emergency Use

A Milestone in Global Health: A New Polio Vaccine Approved for Emergency Use

While substantial progress has been made in the fight against this disease, certain strains of the virus, particularly circulating vaccine-derived poliovirus (cVDPV), a strain that emerges when the weakened virus in oral vaccines mutates back into a more virulent form, continue to circulate in regions with suboptimal ...

ByB Medical Systems


RVx201 Herpes Vaccine

RVx201 Herpes Vaccine

Original Research - Intramuscular Vaccination With the HSV-1(VC2) Live-Attenuated Vaccine Strain Confers Protection Against Viral Ocular Immunopathogenesis Associated With γδT Cell Intracorneal Infiltration - published by Frontiers in Immunology on November 15, 2021 - provides proof of concept for the Company's HSV-1 ...

ByRational Vaccines, Inc.


FluGen Announces Publication of Positive Results from Phase 2 Human Challenge Study of Its M2SR Vaccine Candidate Against Highly Drifted Strain of H3N2 Influenza Virus

FluGen Announces Publication of Positive Results from Phase 2 Human Challenge Study of Its M2SR Vaccine Candidate Against Highly Drifted Strain of H3N2 Influenza Virus

“Current vaccines are strain-specific and in recent years they have had low efficacy against H3N2 influenza, especially when the vaccine is mismatched to circulating virus,” said Dr. ...

ByFluGen, Inc.


FluGen Awarded US Department of Defense Funding to Conduct Clinical Study Evaluating Investigational M2SR Flu Vaccine and Current Standard-of-Care High Dose Vaccine

FluGen Awarded US Department of Defense Funding to Conduct Clinical Study Evaluating Investigational M2SR Flu Vaccine and Current Standard-of-Care High Dose Vaccine

Study is the Company’s first trial evaluating ability of M2SR and the current licensed standard of care to protect against drifted virus strains, and its second study in older adults, a population most vulnerable to mortality from flu – Safety and immunogenicity study expected to begin in Q2 2022 – MADISON, Wis., July 1, 2021 /PRNewswire/ — FluGen, Inc., ...

ByFluGen, Inc.


Your Herd Vaccinations May not Always be Successful? Why?

Your Herd Vaccinations May not Always be Successful? Why?

The vaccine never makes it into the animal The virus or bacteria is a different strain than the vaccine. For example, most IBR vaccines protect 2 strains of the virus and there is no cross-protection for the other strains. ...

ByAmelicor: a Division of DHI Computing Service, Inc


Intramuscular vaccination of mice with the human herpes simplex virus type-1(HSV-1) VC2 vaccine, but not its parental strain HSV-1 (F) confers full protection against lethal ocular HSV-1 (McKrae) pathogenesis

Intramuscular vaccination of mice with the human herpes simplex virus type-1(HSV-1) VC2 vaccine, but not its parental strain HSV-1 (F) confers full protection against lethal ocular HSV-1 (McKrae) pathogenesis

We have previously shown that the HSV-1 VC2 vaccine strain is protective in mice and guinea pigs against genital herpes infection following vaginal challenge with HSV-1 or HSV-2. In this study, we evaluated the efficacy of VC2 intramuscular vaccination in mice against herpetic keratitis following ocular challenge with lethal human clinical ...

ByRational Vaccines, Inc.


Possible role of molecular mimicry in pathogenesis of Ebola virus: implications for a rational vaccine design

Possible role of molecular mimicry in pathogenesis of Ebola virus: implications for a rational vaccine design

Ebola Virus (EBOV) presents a challenge for vaccine development because immune correlates of protection in humans are not well known. ...

ByInderscience Publishers

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