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Vascular Graft Articles & Analysis

8 articles found

Susceptibility of ePTFE vascular grafts and bioengineered human acellular vessels to infection

Susceptibility of ePTFE vascular grafts and bioengineered human acellular vessels to infection

Background: Synthetic expanded polytetrafluorethylene (ePTFE) grafts are routinely used for vascular repair and reconstruction but prone to sustained bacterial infections. ...

ByHumacyte, Inc.


Development of a Bioartificial Vascular Pancreas

Development of a Bioartificial Vascular Pancreas

To address these limitations, an islet transplantation approach using an acellular vascular graft as a vascular scaffold has been developed, termed the BioVascular Pancreas (BVP). To create the BVP, islets are seeded as an outer coating on the surface of an acellular vascular graft, using fibrin as a hydrogel ...

ByHumacyte, Inc.


An Early Study on the Mechanisms that Allow Tissue-Engineered Vascular Grafts to Resist Intimal Hyperplasia

An Early Study on the Mechanisms that Allow Tissue-Engineered Vascular Grafts to Resist Intimal Hyperplasia

Abstract : Intimal hyperplasia is one of the prominent failure mechanisms for arteriovenous fistulas and arteriovenous access grafts. Human tissue-engineered vascular grafts (TEVGs) were implanted as arteriovenous grafts in a novel baboon model. ...

ByHumacyte, Inc.


Effect of endothelium mimicking self-assembled nanomatrices on cell adhesion and spreading of human endothelial cells and smooth muscle cells

Effect of endothelium mimicking self-assembled nanomatrices on cell adhesion and spreading of human endothelial cells and smooth muscle cells

These findings would facilitate the development of novel vascular grafts, heart valves, and cell based therapies for cardiovascular diseases. ...

ByEndomimetics


Five Year Outcomes in Patients with End Stage Renal Disease Who Received a Bioengineered Human Acellular Vessel for Dialysis Access

Five Year Outcomes in Patients with End Stage Renal Disease Who Received a Bioengineered Human Acellular Vessel for Dialysis Access

Objective: Patients with end stage renal failure who require haemodialysis suffer morbidity and mortality due to vascular access. Bioengineered human acellular vessels (HAVs) may provide a haemodialysis access option with fewer complications than other grafts. ...

ByHumacyte, Inc.


Surgical management of an infected external iliac artery interposition graft with a bioengineered human acellular vessel

Surgical management of an infected external iliac artery interposition graft with a bioengineered human acellular vessel

ABSTRACT Infection of prosthetic vascular grafts can manifest as pain, pseudoaneurysms, or arterial insufficiency in the leg. ...

ByHumacyte, Inc.


Injection techniques for bulk cell seeding decellularised vascular scaffolds

Injection techniques for bulk cell seeding decellularised vascular scaffolds

Tissue engineering small diameter vascular grafts requires excessive culture times to produce an appropriate extracellular matrix (ECM). ...

ByInderscience Publishers


A nitric oxide releasing, self assembled peptide amphiphile matrix that mimics native endothelium for coating implantable cardiovascular devices

A nitric oxide releasing, self assembled peptide amphiphile matrix that mimics native endothelium for coating implantable cardiovascular devices

Introduction Cardiovascular disease is the leading cause of death in the United States [1]. Currently, stents and vascular grafts are the primary therapeutic methods for treatment of cardiovascular diseases. ...

ByEndomimetics

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