Symple Surgical Inc.

Symple Surgical is an exciting start-up Medical Device company focused on developing novel therapeutic technologies through controlled Microwave Ablation. Our technologies are thoughtfully designed to be familiar and easy to use by the operator while providing automated control, feedback, and safety for the patient. Symple Surgical’s first product offering is the DirectAblate GRIZZLYTM Microwave Ablation SystemTM. Through the ground-breaking therapy of directed microwave ablation of pre-cancerous Barrett’s cells, we are focused on helping millions of patients worldwide living with Barrett’s Esophagus and the subsequent advancement to esophageal adenocarcinoma (EAC). While multiple clinical studies have demonstrated that radiofrequency ablation for treatment of Barrett’s Esophagus is incompletely effective in 25% of patients studied, the novel utilization of a superior microwave ablation mechanism will overcome these difficult to treat patients.