heparin-binding Downloads
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Sepsis is the body’s systemic inflammatory response to infection and can progress to severe sepsis, septic shock and ultimately multiple organ failure and death. Early diagnosis and appropriate treatment of severe sepsis is vital to improve the patient’s chance of survival. ...
Human CXCL4, additionally known as Platelet-factor 4, is a 70 amino acid protein that is released by activated platelets to promote coagulation. CXCL4 binds to the G protein-coupled receptor CXCR3-B, found in kidney, heart and liver tissue, but a canonical signaling receptor is still unknown. CXCL4 readily binds to heparin-like molecules and glycoproteins and is a regulator of endothelial and ...